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Research

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research Effect of dose reduction of dutasteride in combination with alpha-blockers in patients with lower urinary tract symptoms/benign prostatic enlargement

2 citations , April 2024 in “Urology Annals”

Taking dutasteride every other day works as well as daily and better preserves sexual function.

Predstanormix Duo: A New Domestic Combination Drug for Treating Lower Urinary Tract Dysfunction Symptoms Associated with BPH

research Predstanormix Duo – a new domestic combination drug for the treatment of lower urinary tract dysfunction symptoms associated with BPH.

June 2025 in “Experimental and Сlinical Urology”

This research found that the new combination drug Predstanormix Duo, with dutasteride and tamsulosin, is bioequivalent to established treatments for benign prostatic hyperplasia, showing similar pharmacokinetics and safety, potentially improving treatment availability and adherence in high-risk patients.

research The ability of melatonin to influence oxidative stress and lower the dose of prednisolone in patients with alopecia areata

June 2006 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences”

This study found that melatonin may reduce the dose of prednisone needed for treating alopecia areata and its associated side effects by attenuating free radical damage on the immune system.

The Ability of Nutrient Antioxidants to Influence Oxidative Stress and Lower the Dose of Prednisolone in Patients with Alopecia Areata

research The Ability of Nutrient Antioxidants to Influence Oxidative Stress and Lower the Dose of Prednisolone in Patients with Alopecia Areata

1 citations , March 2017 in “Al-maǧallaẗ al-’irāqiyyaẗ li-l-’ulūm al-ṣaydalāniyyaẗ/Iraqi journal of pharmaceutical sciences”

This study suggests that using nutrient antioxidants can significantly reduce the dose of prednisolone needed in alopecia areata patients while potentially enhancing hair growth and mitigating side effects.

research The Ability of Nutrient Antioxidants to Influence Oxidative Stress and Lower the Dose of Prednisolone in Patients with Alopecia Areata

March 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)”

This study suggests that using vitamin A, vitamin E, and vitamin C for two months may enable a reduction in corticosteroid dosage for alopecia areata, potentially mitigating associated side effects.

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Community Join

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community Does Creatine lower estrogen levels?

4 upvotes 5 years ago

Finasteride is being used for hair loss, and there is concern that creatine might raise DHT levels, potentially reducing finasteride's effectiveness. A dermatologist's guide advises avoiding creatine.

community Does Pyrilutamide lowers sebum production?

2 upvotes 9 months ago

Pyrilutamide's effect on sebum production and scalp inflammation is unclear, with users noting no significant changes. Isotretinoin is mentioned as effective for reducing sebum, while Dutasteride and various shampoos have limited impact on oiliness and seborrheic dermatitis.

community How come i see lower dose fin, when 1mg is recommended

in Treatment 6 upvotes 4 months ago

People are using lower doses of finasteride than the recommended 1mg daily due to concerns about side effects, cost, and new data suggesting lower doses can be nearly as effective. Some users report stability or slight improvements with lower doses, but the effectiveness compared to 1mg daily is debated.

community Finasteride Usage at Lower Doses Debate?

3 upvotes 9 months ago

Topical finasteride at low doses may reduce side effects compared to oral use, but its effectiveness is debated. Some users report benefits with low-dose topical applications, while others suggest sticking to the prescribed 1mg oral dose for better results.

community Dutasteride mesotherapy to lower dut dose

in Finasteride/Dutasteride 1 upvotes 1 year ago

The conversation is about a user considering reducing their dutasteride dose due to side effects like lower libido and watery semen. They plan to use dutasteride mesotherapy every three months to maintain hair while reducing systemic DHT suppression.

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Learn

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learn Hair Transplant

Why are hair transplants cheaper in Turkey? Hair transplants are cheaper in Turkey due to lower operational costs and high competition.
How many grafts do I need for a receding hairline in a hair transplant? You typically need 800 to 2,500 grafts for a receding hairline.

learn Cetirizine

How does cetirizine reduce inflammation linked to hair loss? Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.

learn Metformin

Does metformin help control DHT levels that trigger androgenic alopecia? Metformin has been shown to lower circulating androgens in women with PCOS, but no published study has measured scalp DHT, 5-alpha reductase activity in the follicle, or hair density in anyone taking it — so its effect on pattern hair loss is untested, and it is not a DHT blocker.

learn Follistatin

How does follistatin compare to finasteride or dutasteride for treating androgenic alopecia? Finasteride and dutasteride are prescription drugs with large controlled trials showing they lower DHT and slow androgenic hair loss, at the cost of documented hormonal side effects; follistatin targets a different, regenerative pathway but has only one small phase 1 human trial behind it, so it is experimental with unknown safety rather than a comparable alternative.

learn Overview

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Epidermal Growth Factor

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