The Ability of Nutrient Antioxidants to Influence Oxidative Stress and Lower the Dose of Prednisolone in Patients with Alopecia Areata
March 2017
in “
DOAJ (DOAJ: Directory of Open Access Journals)
”
Studysummary This study suggests that using vitamin A, vitamin E, and vitamin C for two months may enable a reduction in corticosteroid dosage for alopecia areata, potentially mitigating associated side effects. Our plain-language summary of this paper — not a Tressless recommendation.
This study investigated the impact of nutrient antioxidants (vitamins A, E, and C) on reducing the dose of prednisolone in patients with alopecia areata. The findings indicated that a two-month therapy with these antioxidants allowed for a reduction in prednisolone dosage from 100 mg to 10 mg every other day, while also enhancing hair growth. The antioxidants appeared to mitigate the damaging effects of free radicals on the immune system, thereby reducing immune complex deposition. This suggested that nutrient antioxidants could play a significant role in protecting the immune system and minimizing the side effects associated with high doses of corticosteroids.
