September 2001 in “Connective tissue” Type XII and XIV collagens help maintain hair follicle structure in bovine skin.
2 citations
,
July 2011 in “International Journal of Dermatology” EPF can occur without visible pustules.
41 citations
,
April 2009 in “Journal of comparative neurology” P2X3-IR fibers are widespread in rat skin and likely help detect pain.
12 citations
,
January 1994 in “PubMed” Elastic fiber arrangement in mammal skin varies by hair density and body region.
37 citations
,
May 2021 in “Frontiers in Cell and Developmental Biology” The study investigated the origins and roles of Ng2+ perivascular cells in mouse skin development and wound healing. It found that Ng2 labeled most perivascular cells in both developing and adult mouse skin, more so than other markers. These cells were categorized into four populations based on Pdgfrα and Pdgfrβ expression. Lineage tracing revealed that Ng2+ cells in embryonic and neonatal skin contributed to various cell types but not interfollicular fibroblasts. Papillary fibroblasts (Lrig1+) gave rise to Ng2+ cells in the upper dermis, while reticular fibroblasts (Dlk1+) were the source in the lower dermis. In adult skin wounds, Ng2+ cells only contributed to blood vessel-associated cells, maintaining perivascular heterogeneity during repair. The study concluded that Ng2+ perivascular cells are a heterogeneous, lineage-restricted population primarily recruited from papillary or reticular fibroblasts during tissue regeneration.