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    GlossaryHair Follicle Loss

    permanent destruction or degeneration of hair-producing skin structures

    Hair Follicle Loss refers to the permanent destruction or degeneration of hair follicles, which are the small structures in the skin responsible for hair growth. This condition can result from various factors, including genetic predisposition, autoimmune disorders like alopecia areata, or physical damage to the scalp. Once hair follicles are lost, they typically cannot regenerate, leading to permanent hair loss in the affected areas.

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      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

      learn KY19382

      compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

      learn Stemoxydine

      chemical from L'Oreal that encourages hair to enter growth phase

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

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      community Hair loss treatment rabbit hole [OC]

      in Satire  317 upvotes 2 years ago
      Hair loss treatments, ranging from topical minoxidil and finasteride to taking hormones such as estradiol or nandrolone, as well as a controversial suggestion of an orchiectomy. A hair system is also mentioned as an alternative solution.

      community Please explain this Minoxidil phenomena

      in Minoxidil  60 upvotes 1 year ago
      The post discusses the difference in effects of Minoxidil (Min) on scalp and facial hair. The user questions why Min-induced hair growth on the scalp is temporary, while facial hair growth seems permanent, even after stopping Min. They propose theories, including different Min mechanisms on body and facial hair, the role of DHT, and the possibility of not achieving fully terminal hair. The responses include personal experiences and theories about Min's effects on hair growth.

      community Why balding gets worse in every generation?

      in Chat  81 upvotes 5 months ago
      Balding seems to worsen with each generation, possibly due to stress, diet, and environmental factors. The user started treatments like Minoxidil and finasteride.