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Glossary Loose Anagen Hair Syndrome

hair is easily and painlessly pulled out during growth phase

Loose Anagen Hair Syndrome (LAHS) is a condition where hair is easily and painlessly pulled out because it is not properly anchored in the hair follicle during the anagen (growth) phase. This typically results in diffuse hair thinning and shedding, primarily affecting children, but it can also occur in adults. The hair often appears thin, fine, and may not grow long.

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Research

5 / 1000+ results

research A girl with loose anagen hair syndrome and concurrent uncombable hair syndrome

3 citations , January 2020 in “JAAD Case Reports”

This report describes a patient with symptoms suggestive of both loose anagen hair syndrome and uncombable hair syndrome, adding to previous instances of overlapping features between these conditions.

research Loose anagen hair syndrome

40 citations , January 2010 in “International Journal of Trichology”

This review discusses the diagnostic criteria and guidelines for managing loose anagen syndrome and differentiating it from non-scarring alopecias, but it reports no new clinical results.

research LOOSE ANAGEN SYNDROME AND LOOSE ANAGEN HAIR

25 citations , October 1996 in “Dermatologic Clinics”

This article discusses loose anagen syndrome, highlighting its characteristics, diagnostic methods, and spontaneous improvement over time, but provides no new clinical results.

research Loose Anagen Hair Syndrome in Black‐Haired Indian Children

8 citations , August 2013 in “Pediatric Dermatology”

This article reviews loose anagen hair syndrome, an inheritable hair disorder affecting children and sometimes adults, but does not report any new clinical results.

research Heterozygous KRT32 variant is responsible for autosomal dominant loose anagen hair syndrome

May 2025

In this study, researchers identified the c.296C>T (p.T99I) variant in the KRT32 gene, which co-segregates with loose anagen hair syndrome, and found it decreases binding affinity to KRT82, potentially weakening hair anchorage.

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Community Join

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community Pattern hair loss before the age of 35 is associated with higher chances of prostate cancer, cardiovascular diseases, and metabolic syndrome later in life

1075 upvotes 3 months ago

Pattern hair loss before age 35 may be linked to higher risks of prostate cancer, cardiovascular diseases, and metabolic syndrome later in life. Finasteride is discussed as a treatment that may lower PSA levels and potentially prevent prostate issues.

community The truth about Dutasteride (w/ sources)

in Finasteride/Dutasteride 52 upvotes 3 years ago

The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.

community Huberman tweet about finasteride

in Finasteride/Dutasteride 278 upvotes 2 years ago

The conversation is about the side effects of finasteride, including Post Finasteride Syndrome, with varied personal experiences and differing views on the credibility of information sources. Some participants also discuss using minoxidil as a hair loss treatment.

community risks with finasteride and dutasteride

138 upvotes 1 year ago

Finasteride and dutasteride have potential risks, including post-finasteride syndrome, but are commonly used for hair loss. RU58841, minoxidil, and needling are suggested as alternatives, though all treatments carry risks.

community Proof DHT is not the main cause of hair loss. TRPS1 Gene and Protein might be. PP405 won’t work. AMP-303 might!

153 upvotes 6 months ago

Hair loss may be linked to the TRPS1 gene and protein, not just DHT. Amplifica's AMP-303 targets mesenchymal stem cells and shows promise in treating hair loss, unlike Pelage's PP405.

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Learn

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learn Hair Transplant

Will I continue to lose hair after a hair transplant? You may continue to lose non-transplanted hair after a hair transplant.
Will transplanted hair fall out after a hair transplant? Transplanted hair is permanent but may temporarily shed before new growth occurs.

learn Scalp Micropigmentation

What if I lose more hair in the future after scalp micropigmentation? Scalp micropigmentation can be adjusted to cover new areas of hair loss.

learn RU58841

Will I lose my hair if I stop using RU58841? (Spoiler: I might.) There is no published human trial of stopping RU58841; community members commonly report shedding within weeks to months, and androgen biology suggests miniaturization would resume once the topical anti-androgen is withdrawn.