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research The effect of long‐chain monoenes on prostaglandin E₂ synthesis by rat skin

8 citations , July 1977 in “Lipids”

This study found a negative correlation between dietary monoene levels, particularly oleic acid, and the capacity for PGE₂ synthesis in rat skin, with the most severe skin issues noted in those fed Zephyr rapeseed oil.

research Surface Lipids as Multifunctional Mediators of Skin Responses to Environmental Stimuli

105 citations , January 2010 in “Mediators of Inflammation”

This article reviews the role of skin surface lipid in mediating environmental stressors and discusses potential therapeutic interventions, reporting no new experimental findings.

research Emerging 3D bioprinting applications in plastic surgery

15 citations , January 2023 in “Biomaterials Research”

This review explores the application and implications of 3D bioprinting in plastic surgery but reports no new clinical results, emphasizing its potential benefits and challenges for future research.

research The Suppression of Very Long Chain Fatty Acids Is Associated with Skin Carcinogenesis

March 2020 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study suggests that the expression of VLCFA biosynthesis genes is suppressed in skin hyperplasia and cancer, which could influence keratinocyte function.

research Very-long-chain Acyl-CoA Synthetases

191 citations , November 2007 in “Journal of Biological Chemistry”

This review discusses the acyl-CoA synthetase very-long-chain (ACSVL) enzyme family, including its biochemical characteristics, tissue expression, and involvement in lipid metabolism, but presents no new experimental results.

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community Fats on your Head to Stop Hair Loss?

140 upvotes 2 years ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community Ben Greenfield Podcast : CHK-Cu & C-60

4 upvotes 5 years ago

CHK-Cu (copper peptide) and C-60 (branched carbon chain) are discussed as potentially more effective than minoxidil for hair regrowth. Some users are skeptical about the claim that DHT isn't the root cause of hair loss, and others are trying these products to see if they work.

community My progress after 4-5 months of taking meds

414 upvotes 7 months ago

The user experienced positive hair regrowth after 4-5 months using oral minoxidil (10mg) and finasteride (1mg) without side effects. Concerns were raised about the high dosage of minoxidil and potential long-term health risks.

community Another blow to the cursed baldness

in Research/Science 91 upvotes 11 months ago

A South Korean company, Therazyne, has developed a promising hair loss treatment using a WNT chain surrogate that binds to Frizzled 7, with human follicle testing expected soon. Current treatments like minoxidil and finasteride are not seen as cures, and while optimism exists for future solutions like PP405, approval processes are lengthy.

community 2 years after my HT. I couldn’t live with my hair anymore. It took so much effort every morning to style it properly, but just one gust of wind or a bit of rain was enough to ruin it for the rest of the day. I also really disliked how it looked in photos. I'm 32, so I still felt too young for this.

in Transplants 331 upvotes 1 year ago

A 32-year-old had a hair transplant in Istanbul for 2500€, using 2800-3000 grafts, and is not using finasteride or other medications long-term. The user is satisfied with the results but acknowledges the possibility of needing another transplant in the future.

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