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research Long-term time-lapse multimodal intravital imaging of regeneration and bone-marrow-derived cell dynamics in skin

18 citations , September 2013 in “Technology”

This study introduces a new multimodal imaging technology to visualize and quantify cell dynamics in natural skin over long durations, demonstrated in GFP bone marrow-transplanted mice, to study dynamic skin regeneration.

research The long-term effect of specific type II 5alpha-reductase inhibition with finasteride on bone mineral density in men: results of a 4-year placebo controlled trial.

37 citations , May 2002 in “PubMed”

In this study, long-term use of finasteride did not negatively impact bone mineral density in men with benign prostatic hyperplasia over a 4-year period.

research Bone mineral density in patients with alopecia areata treated with long-term intralesional corticosteroids.

14 citations , February 2013 in “PubMed”

This study found that 50% of patients with patchy alopecia areata who underwent chronic intralesional triamcinolone acetonide therapy had abnormal bone mineral density, suggesting the need for monitoring and preventive measures.

research The Long-Term Effect Of Specific Type II 5α-Reductase Inhibition With Finasteride on Bone Mineral Density in Men: Results of a 4-Year Placebo Controlled Trial

11 citations , May 2002 in “The Journal of Urology”

This study reports that long-term use of finasteride does not affect bone mineral density in men with benign prostatic hyperplasia over a four-year period.

research Bone Health Risks Associated with Finasteride and Dutasteride Long-Term Use

1 citations , December 2020 in “The World Journal of Men's Health”

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Learn

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learn Hair Transplant

When can I wear a hat after a hair transplant? Wear a loose-fitting hat after 3 to 10 days, but consult your surgeon first.
Is a hair transplant painful? Clinics say local anaesthetic makes the procedure itself mostly comfortable, but the anaesthetic injections sting and soreness for a few days afterwards is common. Pain varies from person to person.

learn GT20029

Are there any known side effects of using GT20029 on the scalp long-term? Long-term side effects are unknown. Trials of up to 12 weeks reported mostly mild scalp effects such as dryness and itching, at rates similar to placebo (Hu et al. 2025).

learn Stem Cell Factor

Are stem cell factor products safe for long-term scalp use? Long-term safety of stem cell factor scalp products has not been studied in people; the one human trial of injected stem cell factor reported skin reactions and lasting dark patches.

learn Alfatradiol

How long should I wait to see if Alfatradiol is working for me? The one randomised trial and community reports both point to waiting at least 3 to 6 months. That trial, in about 100 women over six months with no placebo group, found no improvement in hair thickness or density; its authors credited alfatradiol with slowing hair loss.

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Community Join

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community Long-term use of dutasteride may lead to male infertility by persistently impairing semen volume and sperm motility.

in Finasteride/Dutasteride 87 upvotes 1 year ago

Long-term use of dutasteride may impair semen volume and sperm motility, but these effects are often reversible after stopping the drug. Individual reactions vary, and more research is needed to understand the long-term impact on fertility.

community ‘Long term use of fin/dut may be associated with health risks including fatty liver disease, insulin resistance, type 2 diabetes, dry eye disease and potential kidney disease.’

in Research/Science 22 upvotes 2 years ago

Long-term use of finasteride and dutasteride may be linked to health risks like fatty liver disease, insulin resistance, type 2 diabetes, dry eye disease, and potential kidney disease. Some users believe the risks are low and the medications are generally safe.

community How long for 0.5mg dut sides to go away

in Treatments 63 upvotes 1 year ago

The user experienced reduced libido and erectile issues after taking 0.5mg dutasteride twice a week for 3-4 weeks. They are concerned about how long these side effects will last.

community 10+ long year fin users share your story

in Finasteride/Dutasteride 63 upvotes 1 year ago

Long-term finasteride users report maintaining or regrowing hair, often using additional treatments like minoxidil, low-level laser therapy, and ketoconazole shampoo. Most experience minimal side effects, though some report issues like erectile dysfunction.

community Dutasteride likely reduces Bone Mineral Density

in Research/Science 6 months ago

Dutasteride may reduce bone mineral density, but there's no increased risk of osteoporosis or fractures compared to finasteride. Users suggest resistance training to counter potential bone effects.

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