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research Morphometric changes of hair follicles in rat excisional wounds treated by Hirudo verbana extract

February 2026 in “The Animal Biology”

In this animal study, Hirudo verbana leech extract significantly improved hair follicle regeneration and accelerated wound healing in rats, demonstrating potential as a safe and effective agent for skin repair due to its bioactive compounds with regenerative and anti-inflammatory properties.

research Building and Maintaining the Skin

22 citations , October 2021 in “Cold Spring Harbor Perspectives in Biology”

This review discusses the interactions and signals affecting skin stem cells and their environments but reports no new experimental results; the authors highlight the need for understanding these processes to enhance tissue rejuvenation and repair.

research Mechanisms of tolerance and potential therapeutic interventions in Alopecia Areata

12 citations , May 2017 in “Pharmacology & therapeutics”

This review discusses the mechanisms underlying immune tolerance failure in alopecia areata and highlights potential therapeutic avenues for restoring hair growth and achieving sustained remission, but reports no new clinical results.

research Local IL-17 orchestrates skin aging

1 citations , January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

This study found that targeting IL-17 signaling in aged skin reduces inflammation and delays age-related traits, suggesting a potential strategy to prevent age-associated skin ailments.

research Skin Changes after Subcutaneous Injection of Epinephrine

October 1933 in “Experimental Biology and Medicine”

In this study, subcutaneous injections of epinephrine in rats led to skin changes ranging from hair loss to necrosis, suggesting these effects were due to the epinephrine itself.

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Community Join

5 / 657 results

community John Cena Says Hair Transplant 'Changed The Course Of My Life' and maintains with daily routine that includes "red-light therapy, minoxidil, vitamins, shampoo"

in Transplants 2620 upvotes 1 year ago

John Cena attributes his improved life and career to a hair transplant and maintenance routine with red-light therapy, minoxidil, vitamins, and shampoo. Users discuss the effectiveness and side effects of finasteride, with mixed opinions on its necessity.

community 5-Months Update: Minoxidil + Red Light Therapy + Lifestyle Changes

1023 upvotes 1 year ago

The user reported positive hair regrowth after 5 months using Minoxidil, red light therapy, and lifestyle changes, including dietary improvements and stress reduction. They chose natural supplements like saw palmetto and beta-sitosterol over pharmaceutical DHT inhibitors like finasteride.

community Switched Finasteride Brands, Hair, Scalp and Skin Declining

in Finasteride/Dutasteride 10 upvotes 1 year ago

Switching finasteride brands from Teva to Proscar led to hair and skin issues, suggesting possible differences in effectiveness or quality. Users recommend returning to the original brand that worked well.

community KX-826 , a small change in the pipeline

in Research/Science 6 upvotes 7 months ago

KX-826 is undergoing trials for hair loss treatment, showing similar effectiveness between 0.5% and 1.0% dosages, with mild side effects compared to finasteride. Users discuss combining KX-826 with other treatments like minoxidil and clascoterone for better results.

community Regrowth with only Nizoral and Lifestyle Changes; focusing on scalp health & nervous system

89 upvotes 7 months ago

The user reported subtle hair regrowth by focusing on scalp health and lifestyle changes, using Nizoral shampoo and methods to reduce inflammation and cortisol, without using finasteride, minoxidil, or other common treatments. Opinions in the conversation varied, with some skeptical of the results and others acknowledging the potential benefits of addressing scalp health and inflammation.

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Learn

4 / 801 results

learn Stem Cell Factor

learn Overview

learn Hair Transplant

Does hair grow back in the donor area after a hair transplant? Hair does not grow back in the donor area after extraction during a hair transplant.

learn Azelaic Acid

Is azelaic acid safe to use daily long-term? Azelaic acid has a long tolerability record on facial skin in acne and rosacea, where side effects are local and usually mild — but for daily long-term scalp use the only trial is one six-month study in 26 women, in which mild itching was the main adverse effect, so long-term scalp safety is not established.

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Clinics

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Experts

1 / 3 results

35
SMP Specialist
Noelle Skin
Nice, France

Noelle Skin