October 2023 in “Journal of pharmaceutical investigation” In this study, researchers found that among healthy Korean males, the clearance of finasteride was about 34% lower in individuals with the CYP3A5*3 homozygous allele compared to other genotypes, suggesting dosage adjustments may be necessary considering CYP3A5 and ALT levels to avoid adverse effects.
1 citations
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October 2024 in “The American Journal of Gastroenterology” This case study suggests that the use of the dietary supplement Nutrafol may have led to drug-induced liver injury in a 26-year-old woman, as evidenced by increased liver enzymes and bilirubin levels which improved after stopping the supplement.
63 citations
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April 2017 in “Acta psychiatrica Scandinavica” This study observed that higher prenatal androgen loads were associated with more severe alcohol dependence in male patients and linked to behaviors of pregnant women that may influence their children’s androgen exposure.
16 citations
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March 2020 in “Journal of The American Academy of Dermatology” This abstract discusses the efficacy of spironolactone, cyproterone acetate, and flutamide in treating female pattern hair loss, noting that flutamide use requires caution due to potential liver toxicity, especially at high doses.
8 citations
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April 2020 in “Journal of The American Academy of Dermatology” This article discusses the potential of oral bicalutamide as a promising treatment for female pattern hair loss and reports no new clinical results.
