October 2025 in “The American Journal of Gastroenterology” In this case report, acute liver failure was attributed to a 34-year-old woman's high-dose zinc supplementation taken for three weeks, illustrating that even commonly used supplements can lead to serious conditions like liver failure.
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February 2022 in “Terapevtičeskij arhiv” This case report describes severe liver injury in a young patient after prolonged overuse of vitamin A, which resolved after cessation.
January 2025 in “Case Reports in Gastrointestinal Medicine” This case report presented by the authors provides the first evidence of severe liver failure associated with the use of topical minoxidil, emphasizing the potential for hepatotoxicity even from drugs with minimal systemic absorption.
This case study described a young man who experienced acute liver failure requiring a transplant after taking Roaccutane for six weeks for severe acne.
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February 2016 in “Scientific Reports” This study reports the creation of rat liver stem cell lines that can differentiate into hepatocytes and suggests they might be useful for pharmacological and regenerative medicine applications.