Roaccutane Induced Acute Liver Failure
August 2013
TLDR Roaccutane can cause severe liver damage.
This case study described a young man who developed acute liver failure after taking Roaccutane (Isoretinoin) for six weeks to treat severe acne. Despite stopping the medication upon noticing jaundice, he presented with acute liver failure two months later, necessitating a liver transplant. Roaccutane, a vitamin A-like drug, was known to cause side effects such as birth defects, liver problems, hair loss, and increased triglyceride levels, with less common reports of depression, suicide, and inflammatory bowel disease.