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Did you mean Liquid Chromatography-Tandem Mass Spectrometry?

Glossary Liquid Chromatography-Tandem Mass Spectrometry

combines separation and identification of compounds in samples

Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) is an advanced analytical technique used to identify and quantify compounds in a sample. It combines liquid chromatography, which separates the mixture into its individual components, with tandem mass spectrometry, which provides detailed information about the molecular structure and quantity of each component. This method is highly sensitive and precise, making it valuable in fields like pharmacology, biochemistry, and environmental science.

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research Metabolic study of androsta-1,4,6-triene-3,17-dione in horses using liquid chromatography/high resolution mass spectrometry

17 citations , August 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

This study concluded that the best approach for detecting Androsta-1,4,6-triene-3,17-dione administration in horses is monitoring the metabolites M1b or M4 in urine, detectable up to 77 hours post-administration.

research Determination of the major component of water fraction of katuk (Sauropus androgynous (L.) Merr.) leaves by liquid chromatography–mass spectrometry

7 citations , January 2019 in “Journal of Pharmacy And Bioallied Sciences”

This study identified the major component of katuk leaf water extract as an alkaloid compound with a molecular mass of 406.3131 m/z, named (S, S)-5,5′-amino-4,4′-dihexyl-propyldihydropyrazol-3,3′-one.

research Liquid chromatographic-mass spectrometric method for determination of drug content uniformity of two commonly used dermatology medications in a split-tablet dosage form

3 citations , July 2016 in “Tropical Journal of Pharmaceutical Research”

This study found that the proposed LC-MS/MS method accurately quantified the drug content in split tablets of finasteride and terbinafine, revealing significant variability and suggesting that non-scored tablets should not be split.

research Screening and confirmation methods of the major urinary metabolite of finasteride–carboxy-finasteride by liquid chromatography–mass spectrometry and liquid chromatography–tandem mass spectrometry

1 citations , March 2012 in “Acta Pharmaceutica Sinica B”

This study developed methods for detecting carboxy-finasteride in urine for doping control, demonstrating detection up to 49 hours post-administration with high precision and accuracy.

research Insights From Liquid Chromatography-Mass Spectrometry-Measured Androgens in Indian Women With Polycystic Ovary Syndrome

January 2024 in “Curēus”

This study found that androstenedione was more effective than testosterone in diagnosing hyperandrogenism in women with PCOS when measured by LC-MS/MS.

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community Liquid Chromatography–Mass Spectrometry (LC-MS) VS Enzyme-Linked Immunosorbent Assay (ELISA)

5 upvotes 1 year ago

Finasteride and Nizoral shampoo with Ketoconazole are used for hair loss treatment. Liquid Chromatography–Mass Spectrometry (LC-MS) is recommended over Enzyme-Linked Immunosorbent Assay (ELISA) for more accurate DHT testing.

community Unexpected Serum DHT Elevation after Generic Dutasteride Use.

in Finasteride/Dutasteride 38 upvotes 1 year ago

Switching from finasteride to a generic dutasteride led to unexpectedly high DHT levels, prompting a switch to a reputed brand and consideration of softgel capsules for better absorption. The user plans to retest DHT levels and may return to finasteride if issues persist.

community Dutasteride SAVES your hair follicles: MAJOR BS on people who say it destroyed their hair permanently.

158 upvotes 2 years ago

The conversation discusses the effectiveness of hair loss treatments, specifically finasteride and dutasteride. The conclusion is that dutasteride significantly reduces DHT levels and may be more effective than finasteride for long-term hair retention, with some users reporting personal experiences and side effects.

community Feel like I'm a reasonably good responder

in Is this regrowth? 274 upvotes 2 years ago

The user "OP" reported significant hair regrowth using oral finasteride, oral and topical minoxidil, ketoconazole shampoo, and derma stamping. OP experienced initial shedding but no other side effects.

community hairloss treatment, what to expect (bloodwork)

1 upvotes 11 months ago

The conversation discusses hair loss treatment options, focusing on finasteride and its potential effects on gynecomastia. The user is considering finasteride while managing hormone levels with supplements like boron, vitamin D, zinc, magnesium, and P5P, and is advised to consult an endocrinologist for further evaluation.

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