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research Decision Letter: Human Biallelic MFN2 Mutations Induce Mitochondrial Dysfunction, Upper Body Adipose Hyperplasia, and Suppression of Leptin Expression

January 2017

MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.

Polycystic Ovary Syndrome: A Complex Condition with Psychological, Reproductive, and Metabolic Manifestations That Impacts Health Across the Lifespan

research Polycystic Ovary Syndrome: A Complex Condition with Psychological, Reproductive, and Metabolic Manifestations That Impacts Health Across the Lifespan

926 citations , June 2010 in “BMC Medicine”

Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

research Polycystic Ovary Syndrome and Infertility: An Update

26 citations , July 2021 in “International journal of adolescent medicine and health”

New treatments for PCOS are improving fertility and managing symptoms better.

research A Guide to Studying Human Dermal Adipocytes In Situ

21 citations , March 2018 in “Experimental Dermatology”

The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.

research Harnessing Neuroendocrine Controls of Keratin Expression: A New Therapeutic Strategy for Skin Diseases?

26 citations , May 2014 in “BioEssays”

Using neurohormones to control keratin can lead to new skin disease treatments.

View more "lipolysis regulation" in research →

Community Join

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community How ET-02 Works. Also no proof that it's better than Minoxidil. At least for now.

in Research/Science 44 upvotes 8 months ago

ET-02, a PAI-1 inhibitor, is not proven to be more effective than Minoxidil for hair loss. Other treatments like finasteride, dutasteride, PP405, and AMP-303 are also discussed, focusing on cellular senescence and oxidative stress.

community Minoxidil + Gym + Cutting. Is it bad?

in Minoxidil 38 upvotes 2 years ago

A user is concerned about weight loss stagnation while using minoxidil and finasteride during a calorie-cutting diet. Responses suggest water retention or a weight loss plateau as possible causes.

community FtM: "Aggressive Regemin - Recovery From Norwood-6.5" Minoxodil/Estradiol valerate/Spironolactone. (What will happen in the worst case if CIS male go this way for a year?)

in Progress Pictures 54 upvotes 4 years ago

User "Ant1pal" shares progress pictures of hair regrowth using Minoxidil, Estradiol valerate, and Spironolactone. Users discuss potential side effects and the possibility of localizing estrogen to hair follicles for better treatment.

community The Big Fat Layer II

in Research/Science 26 upvotes 4 years ago

Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.

community I find it funny a bunch of us on here are on drugs for hairloss and maintain clean/healthy lives and then there’s these mf’s in the 90’s juiced to the gills with steroids and have better hair than all of us lol

in Satire 353 upvotes 2 years ago

The conversation is about the effects of steroids on hair loss. Some users believe that steroids can cause hair loss, while others argue that it depends on individual sensitivity to DHT. There is also discussion about the appearance of balding individuals who use steroids.