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Oligomeric Procyanidins in Apple Polyphenol Are Main Active Components for Inhibition of Pancreatic Lipase and Triglyceride Absorption

research Oligomeric Procyanidins in Apple Polyphenol Are Main Active Components for Inhibition of Pancreatic Lipase and Triglyceride Absorption

282 citations , April 2007 in “Journal of Agricultural and Food Chemistry”

Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.

research Lights Triggered Differential Accumulation of Antioxidant and Antidiabetic Secondary Metabolites in Callus Culture of Eclipta Alba L.

64 citations , June 2020 in “PLoS ONE”

Red light boosts beneficial compounds in Eclipta alba cultures.

research The Potential of Clausena Anisata (Willd.) Hook.f. ex Benth Against Propionibacterium Acnes

7 citations , October 2018 in “South African journal of botany”

Clausena anisata may be effective in treating acne due to its ability to fight bacteria, reduce inflammation, and possibly lower sebum production.

research Novel 5α-Reductase Inhibitors: Synthesis, Structure-Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids

18 citations , December 2005 in “Journal of Medicinal Chemistry”

A brominated phenoxy compound effectively inhibits a human enzyme and shows potential for clinical use.

Diagnosis, Management, and Associated Comorbidities of Polycystic Ovary Syndrome: A Narrative Review

research Diagnosis, Management, and Associated Comorbidities of Polycystic Ovary Syndrome: A Narrative Review

April 2024 in “Curēus”

Early detection and comprehensive treatment of PCOS are crucial due to its long-term health impacts and associated risks.

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community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

in Research/Science 134 upvotes 1 year ago

The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

in Research/Science 124 upvotes 2 years ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.