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    GlossaryHedgehog signaling pathway (Hh signaling)

    regulates cell growth and development through protein-receptor interactions

    The Hedgehog signaling pathway is a crucial mechanism in developmental biology that regulates cell growth, differentiation, and tissue patterning. It involves the Hedgehog proteins binding to receptors on cell surfaces, which then trigger a cascade of intracellular events that influence gene expression. This pathway is essential for proper embryonic development and, when dysregulated, can lead to conditions such as cancer and congenital disorders.

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      learn SCUBE3

      a signaling molecule from dermal papilla cells being actively researched

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

      learn Exosomes

      Microscopic delivery system that sends growth-promoting signals to hair follicles

      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin