1 citations
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January 2010 in “International journal of medicinal mushrooms” This study found that Ganoderma lucidum fruiting body powder improved cholesterol profiles and hair follicle health in rats exposed to a tumor-promoting agent, suggesting potential chemopreventive properties against skin abnormalities.
3 citations
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June 2024 in “Journal of Neuroendocrinology” This study observed that many women with PCOS had unfavorable lipoprotein profiles, mostly moderate changes in triglycerides, HDL, and LDL cholesterol, with small LDL particles not being rare and potentially aiding risk assessment.
This study introduced Cadd4, a peptide-based degrader developed using computer-aided drug design, which effectively reduced PCSK9 levels and increased LDL receptor expression, resulting in decreased plasma cholesterol and LDL-C levels in hypercholesterolemic mice, without liver toxicity.
November 2024 in “SKIN The Journal of Cutaneous Medicine” This study observed that patients with severe alopecia areata treated with baricitinib experienced increases in total cholesterol, LDL-C, and HDL-C, consistent with a JAK inhibitor class effect, but the mean increase was modest and lipid-lowering medication initiation was infrequent.
2 citations
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September 2021 in “F1000Research” This study found that the ABCG2 (Q191K) polymorphism increases the risk of hyperuricemia and hypercholesterolemia specifically in young Mexican males.