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GlossaryLaminin-511 (Laminin 10)

protein crucial for hair follicle development and maintenance

Laminin-511, also known as Laminin-10, is a protein found in the extracellular matrix, which provides structural support to cells and tissues. It plays a crucial role in cell adhesion, differentiation, and migration, and is particularly important in the development and maintenance of hair follicles.

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research Re-Investigating the Basement Membrane Zone of Psoriatic Epidermal Lesions: Is Laminin-511 a New Player in Psoriasis Pathogenesis?

13 citations, June 2018 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry”

Laminin-511 may contribute to psoriasis by affecting skin cell growth and survival.

research Spatial And Temporal Control Of Laminin-511 And -332 Expressions During Catagen

6 citations, April 2010 in “Journal of Dermatological Science”

Laminin-511 may help promote hair growth, while laminin-332 does not affect hair loss.

research ILK Modulates Epithelial Polarity and Matrix Formation in Hair Follicles

22 citations, March 2014 in “Molecular biology of the cell”

ILK is essential for proper hair follicle development and structure.

research Laminin-511 Is an Epithelial Message Promoting Dermal Papilla Development and Function During Early Hair Morphogenesis

102 citations, August 2008 in “Genes & Development”

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

research Laminin-511, Inducer of Hair Growth, Is Down-Regulated and Its Suppressor in Hair Growth, Laminin-332 Up-Regulated in Chemotherapy-Induced Alopecia

13 citations, April 2010 in “Journal of dermatological science”

Chemotherapy-induced hair loss is partly due to decreased laminin-511 and increased laminin-332.

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