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This report describes a case of a 5-year-old boy with acute somnolence, alopecia, keratoconjunctivitis, and perioral stomatitis linked to lactic acidaemia.

This review discusses technological advances in liposome systems for drug delivery and reports no new clinical results; it highlights the clinical acceptance and market presence of liposomal products.

Lacto-fermentation changes amino acid profiles in bovine colostrum, but results are inconsistent.

This case report describes a 10-month-old boy with dermatitis, alopecia, and hypotonia who showed dramatic improvement with oral biotin, suggesting a possible defect in biotin absorption or transport.

In this study, biotinidase deficiency in children usually presented with neurological or skin symptoms, while metabolic ketoacidosis and organic aciduria appeared later.