Search

for
Search:

Research

5 / 1000+ results

5alpha-Reductase Inhibitors Dampen L-DOPA-Induced Dyskinesia via Normalization of Dopamine D1-Receptor Signaling Pathway and D1-D3 Receptor Interaction

research 5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction

26 citations , September 2018 in “Neurobiology of Disease”

This study found that both finasteride and dutasteride significantly reduced L-DOPA-induced dyskinesia in a rat model of Parkinson's disease, with dutasteride showing greater effectiveness at lower doses.

research Pregnenolone for the treatment of L-DOPA-induced dyskinesia in Parkinson's disease

2 citations , March 2023 in “Experimental neurology”

In this study, pregnenolone was found to dose-dependently reduce L-DOPA-induced dyskinesias in a rat model of Parkinson's disease, suggesting its potential as a therapeutic target for these dyskinesias.

research Is seborrhea a sign of autonomic impairment in Parkinson's disease?

46 citations , November 1997 in “Journal of Neural Transmission”

Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.

research Effect of 5-alpha reductase inhibitors in animal models of Parkinson’s disease

September 2024 in “Frontiers in Neuroendocrinology”

In this review, the researchers reported that 5α-reductase inhibitors demonstrated neuroprotective effects and reduced dyskinesias in animal models of Parkinson's disease, suggesting their potential for repurposing to manage symptoms in men with PD.

research Le financement du cycle de l'eau en région flamande

January 2005 in “Psychoneuroendocrinology”

In this study, finasteride altered the expression of nine proteins in the rat nucleus accumbens, suggesting new therapeutic targets and mechanisms for its effects on neuropsychiatric conditions.

View more "l-dopa" in research →

Community Join

5 / 539 results

community Has anyone with high prolactin taken meds to lower it and seen hair regrowth?

5 upvotes 8 months ago

High prolactin levels may contribute to hair loss, and some users suggest supplements like mucuna pruriens, vitamin B6, vitamin E, L-Tyrosine, L-Theanine, DIM, and Zinc to lower prolactin. Lifestyle changes to increase dopamine, such as reducing screen time and stress, are also recommended.

community How many are hyper responders to Finasteride?

6 upvotes 4 months ago

The user experienced severe side effects from finasteride, including hormonal imbalances and cognitive issues, leading to a recommendation to stop its use. They plan to follow up with tests to rule out a pituitary tumor and are considering topical treatments as alternatives.

community 5 months into 0.5mg Dutasteride 3x a week + 5mg Oral Minoxidil

in Progress Pictures 58 upvotes 8 months ago

A user is treating hair loss with 0.5mg Dutasteride three times a week, 5mg oral Minoxidil daily, and topical finasteride and minoxidil, seeing some improvement but insufficient density. They are considering increasing Dutasteride dosage and addressing high estradiol levels, while also trying to quit vaping.

community After quitting min and fin I asked AI on how fix the mess I am in and it says:

in Technology 1 year ago

Prolonged use of topical minoxidil and finasteride can lead to neuroendocrine and autonomic dysfunction, causing severe sensitivity and side effects. Recovery involves avoiding these treatments, supporting neurosteroid recovery, calming the sympathetic system, and rebuilding scalp health naturally.

community How finasteride lowers brain's happiness steroid allopregnanolone and causes depression: systemic dihydroprogesterone crosses blood brain barrier, you don't even need finasteride and brain 5ar for that

288 upvotes 1 year ago

Finasteride may lower allopregnanolone levels, potentially affecting mood, but many users report improved mental health due to reduced hair loss. Experiences with finasteride and dutasteride vary, with some experiencing side effects and others finding them beneficial for hair retention and overall happiness.

View more "l-dopa" in community →

Learn

5 / 801 results

learn L-cysteine

What is L-cysteine, and why is it often included in hair growth supplements? L-cysteine supports hair growth by strengthening keratin, the main protein in hair.
Can taking L-cysteine orally really strengthen hair from the inside? L-cysteine may help strengthen hair if there's a deficiency, but results vary.
Does L-cysteine work better alone or when combined with other vitamins and minerals? L-cysteine works better when combined with vitamins and minerals for optimal hair health.
All 5 questions on L-cysteine →

learn L-methionine

learn L-Lysine

learn L-Proline

learn L'Carnitine

View more "l-dopa" in learn →

Experts

— no results

Try a deeper search in experts →

Clinics

— no results

Try a deeper search in clinics →