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GlossaryKeratotic Papules

small, rough skin bumps from excess keratin production

Keratotic papules are small, rough bumps on the skin caused by an overproduction of keratin, a protein that helps protect the skin. These bumps are often associated with conditions like keratosis pilaris, where dead skin cells clog hair follicles, leading to a bumpy texture.

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research Natural Course of Epidermolysis Bullosa Simplex with Mottled Pigmentation in a Japanese Family with the p.P25L Mutation in KRT5

3 citations, January 2019 in “Journal of Dermatology”

The p.P25L mutation in the KRT5 gene causes a rare skin condition that worsens over time and may lead to hair loss starting in young adulthood.

research Sorafenib-Associated Facial Acneiform Eruption

15 citations, December 2014 in “Dermatology and therapy”

Sorafenib can cause facial acne-like eruptions, which improve after reducing the dose or stopping the drug.

research Atlas of Geriatric Dermatology

2 citations, January 2014 in “Springer eBooks”

The book details skin conditions in older adults, their link to mental health, cancer treatment importance, hair loss remedies, and managing autoimmune and itchy skin.

Posters Presented at the 19th Joint Meeting of the International Society of Dermatopathology, March 2–3, 2016, Hilton Crystal City at Washington Reagan National Airport, Arlington, Virginia, USA

research Posters Presented at the 19th Joint Meeting of the International Society of Dermatopathology, March 2–3, 2016, Hilton Crystal City at Washington Reagan National Airport, Arlington, Virginia, USA

July 2016 in “American Journal of Dermatopathology”

The meeting showcased rare skin disease cases, highlighting the need for accurate diagnosis and treatment.

research Disorders of Keratinization

November 2014

The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.

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community My skin is always dry and flakes like chalk (25)

in Transgender 6 upvotes 7 months ago

The user underwent a biopsy two years ago and was diagnosed with keratosis pilaris, leading to hair issues. They tried treatments including Minoxidil, betamethasone, lymecycline, topical Accutane, and dutasteride, as well as diet changes, without improvement in hair thickness or skin dryness.

community What are these spots on my scalp

in Treatment 51 upvotes 4 months ago

A user noticed non-itchy, non-bleeding spots on their scalp while experiencing hair loss. Replies suggest the spots are likely sunspots or liver spots and recommend seeing a dermatologist; hair loss is attributed to male pattern baldness.

community My Experience and a Discourse on "DUPA"

in Treatment 9 upvotes 5 months ago

The user discusses their hair loss experience, exploring various hypotheses including thyroid levels, vitamin D, DHEA, nutritional deficiency, diabetes, seborrheic dermatitis, lack of nutrition to hair follicles, chronic inflammation, female pattern hair loss causes, cortisol, and prolactin levels. They are currently using finasteride, beta-sitosterol, and have tried topical dutasteride and microneedling therapy.

community here is why isotretinoin might cause hair loss and maybe why dupa happens.

in Research/Science 7 upvotes 1 year ago

Isotretinoin may cause hair loss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hair loss.

community Eliminating scalp itch leads to regrowth (and my RU58841 progress)

in Research/Science 62 upvotes 1 year ago

User experienced hair regrowth after eliminating scalp itch with RU58841. Others discussed itch and hair loss connection, and effectiveness of combining RU58841 with 5AR inhibitors.

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