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    Did you mean Keratosis Follicularis?
    Glossary Keratosis Follicularis

    rare genetic skin disorder causing rough, warty papules and plaques

    Keratosis Follicularis, also known as Darier's Disease, is a rare genetic skin disorder characterized by the development of rough, warty papules and plaques, primarily in seborrheic areas such as the scalp, forehead, upper arms, chest, and back. It is caused by mutations in the ATP2A2 gene, which affects calcium regulation in skin cells, leading to abnormal keratinization and skin cell adhesion.

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      research Hair Disorders

      November 2019 in “Harper's Textbook of Pediatric Dermatology”
      This review discusses potential causes of alopecia and hair overgrowth in pediatric patients, detailing diagnostic techniques and treatments, but presents no new research findings.

      research Disorders of Keratinization

      November 2014
      This chapter reviews various skin disorders classified as Mendelian disorders of cornification and reports no new clinical findings, highlighting the complexity of genetics involved in inherited ichthyoses.