39 citations
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January 1997 in “Pharmacology & toxicology” This study found that human keratinocytes' sensitivity and response to vitamin D3 analogues vary based on cell density, serum availability, and calcium concentration.
39 citations
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August 1998 in “FEBS Letters” In this study, researchers identified two novel peptidylarginine deiminases from treated rat keratinocytes, both showing enzyme activity with PAD‐R11 reflecting a characteristic of epidermal enzymes.
16 citations
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August 2019 in “Cell Proliferation” This study found that 3D cultured hair follicle-like constructs, which include keratinocytes and dermal papilla cells, showed improved gene expression and cell interactions relevant to hair follicle development.
November 2022 in “Journal of Investigative Dermatology” This study found that short-term treatment with ROCKi significantly increased keratinocyte stem cell proliferation without affecting their stemness, suggesting a potential safe approach for improving in vitro keratinocyte cultures for clinical applications.
2 citations
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January 2019 in “Methods in molecular biology” This protocol demonstrates that pharmacological inhibition of TGF-β signaling can enhance the proliferative capacity of mouse and human keratinocytes, facilitating their use in skin research and graft preparation.
