98 citations
,
June 2001 in “Journal of biological chemistry/The Journal of biological chemistry”
This study identified a cluster of genes on chromosome 17 related to hair keratin-associated proteins, including 37 genes forming seven multigene families, localized in the hair shaft's upper cortex.
This study found that mutations in type I IRS keratingenes disrupt keratin protein complexes in mice, suggesting crucial roles for these genes in proper hair coat formation.
54 citations
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January 1995 in “Human Molecular Genetics”
This study mapped monilethrix, a hereditary hair and nail disorder, to the type II keratin cluster on chromosome 12q, marking the first primary human hair disorder localization and implicating defects in "hard" keratins.
OP is considering using a keratin gel to improve hair quality and is concerned about its safety and visual impact on a slightly balding crown. Users discuss shampoo frequency, with some suggesting less frequent use for better hair health, but OP prefers regular shampoo and conditioner for silky hair.
A 23-year-old woman with androgenetic alopecia (AGA) is using minoxidil, rosemary oil, and dermastamping for hair loss, and is concerned about the effectiveness of minoxidil. She follows a detailed hair care routine and takes supplements like inositol, magnesium, saw palmetto, iron, multivitamins, vitamin D, and B12.
A person improved hair loss from Norwood 3 to Norwood 2 using a topical formula with minoxidil, dutasteride, and tretinoin, plus oral minoxidil and red light therapy. There is skepticism about the treatment's effectiveness and concerns about misleading comparison photos.