20 citations
,
August 1997 in “PubMed” This study indicates that activating K+ channels in dermal papilla cells alone may not promote hair growth, despite some openers being effective on certain channels.
33 citations
,
May 1991 in “British Journal of Pharmacology” Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.
119 citations
,
June 2005 in “Journal of Molecular and Cellular Cardiology” This article reviews the therapeutic potential of potassium channel openers for various conditions related to metabolic distress but does not report new clinical results; it emphasizes the need for further research.
35 citations
,
March 2005 in “Journal of Investigative Dermatology” In this in vitro study, minoxidil, diazoxide, and the novel compound NNC 55-0118 increased hair follicle growth, supporting deer follicles as a viable bioassay for ATP-sensitive potassium channel modulators.
November 2010 in “Bradford Scholars (University of Bradford)” In this study, the authors reported that NNC55-9216, a selective SUR1 KATP channel opener, stimulated hair follicle growth in culture and enhanced the effects of minoxidil, suggesting a new potential treatment for hair loss.