research A Model for the Turnover of Dihydrotestosterone in the Presence of the Irreversible 5α-Reductase Inhibitors GI198745 and Finasteride
Both drugs lower DHT levels, with GI198745 being more effective.
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research 2-Substituted 4-(Thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
research Steroid Sulfatase Inhibitors
Steroid sulfatase inhibitors could help treat hormone-related disorders and cancers.
research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
research Blood Donors on Medication: An Approach to Minimize Drug Burden for Recipients of Blood Products and to Limit Deferral of Donors
Donors on most medications can donate certain blood products without waiting, except for specific drugs that need a waiting period.
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5 / 183 resultscommunity How long does topical fin reduce scalp DHT?
Topical finasteride reduces scalp DHT effectively, with a suggested application of 1.5ml of 0.03% daily. It binds to scalp enzymes, potentially requiring daily or every other day application for sustained results.
community Warning: finasteride to dutasteride switch
Switching from finasteride to dutasteride can cause significant hair shedding if done abruptly. It's recommended to overlap both treatments and gradually taper off finasteride to minimize shedding.
community Research Backed Dutasteride Simulator (Serum/scalp DHT included for all doses)
A Dutasteride Simulator predicts serum dutasteride, serum DHT, and scalp DHT levels using models from research papers. It simulates various dosing schedules to determine steady-state effects and visualizes outcomes, including hair growth-related scalp DHT suppression.
community Research Backed Dutasteride Simulator (Serum/Scalp DHT included for all doses)
A dutasteride simulator predicts that daily 0.5 mg dosing results in higher DHT suppression compared to less frequent dosing. Twice-weekly dutasteride may be as effective as finasteride 5 mg, providing a balance between efficacy and ease of use.
community Transient and Permanent Effects of Finasteride Use
Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.