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GlossaryNeurosyphilis

infection spreads to nervous system causing severe neurological symptoms

Neurosyphilis is a severe, late-stage manifestation of syphilis, a sexually transmitted infection caused by the bacterium Treponema pallidum. It occurs when the infection spreads to the nervous system, potentially leading to symptoms such as headaches, altered mental status, sensory deficits, and even paralysis. Early diagnosis and treatment with antibiotics are crucial to prevent irreversible damage.

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research Dilated Tonic Pupils with Tabes Dorsalis in Neurosyphilis as First Manifestation of HIV/AIDS: A Video Report

1 citations, March 2018 in “BMJ case reports”

Dilated pupils can be an early sign of HIV/AIDS.

research Syphilitic Alopecia: Report of a Challenging Case and Review of the Literature

December 2020 in “Journal of clinical and investigative dermatology”

A man with syphilitic alopecia and neurosyphilis was successfully treated with penicillin, leading to symptom improvement and resolution of hair loss.

research Syphilis: The Great Imitator

35 citations, January 2019 in “Clinics in Dermatology”

Syphilis has a wide range of symptoms that can look like other diseases, and if not treated, it can progress to a more serious stage, especially in HIV-positive patients.

research Early Diffuse Alopecia in a Neonate with Congenital Syphilis

7 citations, November 2006 in “Pediatric Dermatology”

A newborn with congenital syphilis had unusual hair loss possibly caused by the infection.

research 31-Year-Old Woman With Chronic Daily Headache and Alopecia

1 citations, January 2013 in “Mayo Clinic Proceedings”

A woman's chronic headaches and hair loss were cured by treating her syphilis.

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