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Electrospray Ionization Mass Spectrometry

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Quantitative Analysis of Finasteride Tablets Dissolution Content with Non-Isotopically Labeled Internal Standard by Paper Spray Ionization Mass Spectrometry

research Quantitative Analysis of Finasteride Tablets Dissolution Content with Non-Isotopically Labeled Internal Standard by Paper Spray Ionization Mass Spectrometry

2 citations , September 2018 in “Journal of Separation Science”

PSI-MS quickly and accurately measures finasteride in tablets, helping with quality control.

research Characterization of Spironolactone and Metabolites Derivatized Using Girard's Reagent P with Mass Spectrometry and Ion Mobility Spectrometry

4 citations , May 2024 in “Rapid Communications in Mass Spectrometry”

Girard's reagent P improves detection of spironolactone and its metabolites.

research Improved Forensic Hair Evidence for Drugs of Abuse by Mass Spectrometry

January 2016

Forensic hair analysis for drugs is now more reliable and accurate.

research Simultaneous Determination of Multi-Class Active Pharmaceutical Ingredients by UHPLC-HRMS

2 citations , May 2021 in “Journal of pharmaceutical and biomedical analysis”

A new method was developed to accurately detect and measure 47 different drug ingredients in various products.

Biotransformation of Finasteride by Ocimum Sanctum L., and Tyrosinase Inhibitory Activity of Transformed Metabolites: Experimental and Computational Insights

research Biotransformation of Finasteride by Ocimum Sanctum L., and Tyrosinase Inhibitory Activity of Transformed Metabolites: Experimental and Computational Insights

3 citations , August 2014 in “Steroids”

Fermentation of Finasteride with Ocimum sanctum L. creates new metabolite that inhibits tyrosinase.

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community Why should more people explore the "new frontiers" of treatment (Megathread).

in Treatment 9 upvotes 1 year ago

The conversation discusses exploring new hair loss treatments beyond popular ones like Finasteride, Minoxidil, and Ketoconazole. Specific treatments mentioned include ozone therapy, Dutasteride mesotherapy, RegeneraActiva, microcurrent electrical hair stimulation, Nourkrin, and BioEqua Enercharger.

community Why is dutasteride's volume of distribution so much bigger than finasteride? Is it more lipophilic and crosses barriers better?

in Finasteride/Dutasteride 24 upvotes 1 year ago

Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.

community Finasteride does deplete important nuero-active steroids

in Research/Science 9 upvotes 2 years ago

Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.