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GlossaryElectrospray Ionization Mass Spectrometry

analyzes molecules by converting them into charged particles

Electrospray Ionization Mass Spectrometry (ESI-MS) is a technique used to analyze the mass and structure of molecules by converting them into charged particles (ions) using an electric field. This method is particularly useful for studying large biomolecules like proteins and peptides, as it allows for the gentle ionization of these complex structures without breaking them apart.

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research A Rapid, Simple, Liquid Chromatographic-Electrospray Ionization, Ion Trap Mass Spectrometry Method for the Determination of Finasteride in Human Plasma and Its Application to Pharmacokinetic Study

5 citations , January 2012 in “PubMed”

A new method accurately measures finasteride levels in human plasma.

research Simultaneous Quantitation of Nine Hydroxy-Androgens and Their Conjugates in Human Serum by Stable Isotope Dilution Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry

22 citations , January 2017 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology”

A new method accurately measures nine specific hormones in human blood.

research Determination of Finasteride in Human Plasma by HPLC-MS

1 citations , January 2005 in “Chinese Journal of Hospital Pharmacy”

The method reliably measures finasteride in human plasma.

research Development of Hair Analysis Methods by MALDI-TOF-MS and MALDI-MSI and Evaluation of Cosmetic Treatments

February 2024

The study concluded that the developed method can show how argan, avocado, and coconut oils penetrate and change hair, suggesting these oils are effective in hair treatments.

Quantitative Analysis of Finasteride Tablets Dissolution Content with Non-Isotopically Labeled Internal Standard by Paper Spray Ionization Mass Spectrometry

research Quantitative Analysis of Finasteride Tablets Dissolution Content with Non-Isotopically Labeled Internal Standard by Paper Spray Ionization Mass Spectrometry

2 citations , September 2018 in “Journal of Separation Science”

PSI-MS quickly and accurately measures finasteride in tablets, helping with quality control.

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community Finasteride does deplete important nuero-active steroids

in Research/Science 9 upvotes 2 years ago

Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.