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GlossaryIntermediate Filaments

structural proteins in cells providing mechanical support and stability

Intermediate filaments are a type of structural protein found within cells that help maintain their shape and integrity. They are part of the cytoskeleton, which also includes microtubules and actin filaments, and they provide mechanical support to cells, enabling them to withstand stress and strain.

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research Disulfide Cross-Linked Network Structure of Intermediate Filament and Matrix in Hair and Wool Cortices

4 citations , January 2015 in “Sen'i Gakkaishi”

Hair and wool strength is affected by the number and type of bonds in their protein structures, with hair having more protein aggregates than wool.

research Studies on the Proteome of Human Hair: Identification of Histones and Deamidated Keratins

54 citations , January 2018 in “Scientific reports”

Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.

research Evolution of Trichocyte Keratins

18 citations , January 2018 in “Advances in experimental medicine and biology”

Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.

research Intermolecular Disulfide Cross-Linked Structural Change Induced by Permanent Wave Treatment of Human Hair with Thioglycolic Acid

1 citations , January 2013 in “PubMed”

Permanent wave treatment with thioglycolic acid changes hair structure by altering disulfide bonds.

research The Human Keratins: Biology And Pathology

1398 citations , May 2008 in “Histochemistry and Cell Biology”

Keratins are crucial for cell stability, wound healing, and cancer diagnosis.

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community the ordinary retinol & minoxidil

in Minoxidil 13 upvotes 10 months ago

Using retinol with minoxidil may not be as effective as tretinoin, but retinaldehyde or adapalene could be alternatives. A micro-roller with minoxidil is suggested for better results.

community 1 year results on dut 0.5mg 24M. Big thanks to this community for helping me to fight norwood reaper

in Progress Pictures 63 upvotes 1 year ago

The user achieved significant hair regrowth using only dutasteride, noticing results after 8-9 months despite initial shedding. They did not use minoxidil due to inconvenience but still experienced permanent hair growth.

community When counting hairs, should I be including vellus/baby hairs?

swishyliv in General 95 upvotes 1 month ago

The conversation is about whether vellus hair should be included in hair fall counts, with data showing daily hair loss. The consensus is that shedding, including vellus hair, is normal and within physiological limits.

community Do you guys have very thin hairs that don’t grow where you lost hair?

in Is this regrowth? 7 upvotes 6 months ago

Thin, short hairs often appear in areas of hair loss but may not grow fully despite treatments like finasteride. Some users consider additional treatments like microneedling or hair transplants.

community Chlorine dioxide: An effective product?

in Research/Science 6 upvotes 1 year ago

Chlorine dioxide was discussed as a potential hair growth treatment, with a method involving spraying it on the scalp and covering it with a cap. Concerns were raised about its safety, comparing it to bleach.

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