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Glossary Insulin Resistance

condition where cells don't respond well to insulin

Insulin Resistance (IR) is a condition where the body's cells become less responsive to the hormone insulin, which is crucial for regulating blood sugar levels. As a result, the pancreas produces more insulin to compensate, leading to higher insulin levels in the blood and potentially progressing to type 2 diabetes. This condition is often associated with obesity, physical inactivity, and genetic factors.

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Research

5 / 1000+ results

research Free androgen index (FAI)’s relations with oxidative stress and insulin resistance in polycystic ovary syndrome

14 citations , March 2023 in “Scientific Reports”

This study found that in women with polycystic ovary syndrome, PCOS phenotype and oxidative stress markers were significantly related to free androgen index levels, but insulin resistance was not.

research Association between Insulin Resistance and Cardiovascular Risk Factors in Polycystic Ovary Syndrome Patients

15 citations , April 2018 in “Revista Brasileira de Ginecologia e Obstetrícia”

In this study of women with polycystic ovary syndrome, insulin resistance was associated with obesity, waist circumference, lipid accumulation, and hypertension, with no significant difference in prevalence between different diagnostic methods.

research Acanthosis nigricans in the knuckles: An early, accessible, straightforward, and sensitive clinical tool to predict insulin resistance

6 citations , January 2018 in “Dermato-endocrinology”

This study found that acanthosis nigricans in the knuckles correlates with higher insulin and HOMA-IR values, potentially serving as an early, accessible marker for insulin resistance even without excess weight.

research Role of Insulin Resistance in Males with Early Androgenetic Alopecia

February 2017 in “Clinical dermatology open access journal”

This study found a strong association between insulin resistance and early androgenetic alopecia in males, with insulin resistance increasing alongside alopecia severity and influenced by factors like smoking.

research Metformin improves polycystic ovary syndrome symptoms irrespective of pre-treatment insulin resistance

91 citations , November 2007 in “European journal of endocrinology”

This study found that metformin improved insulin resistance, hyperandrogenemia, anovulation, and acne in PCOS patients, regardless of their level of obesity or initial insulin resistance.

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community Severe copper deficiency, and also zinc deficiency. Looking for testimonials.

2 upvotes 9 months ago

A 36-year-old man with androgenetic alopecia suspects copper and zinc deficiencies may be accelerating hair loss and is supplementing copper to address this. He is also monitoring blood sugar levels due to previous prediabetes concerns and plans to test for insulin resistance.

community Insulins impact on androgen levels

16 upvotes 4 years ago

Controlling insulin levels through intermittent fasting and a low glycemic diet may improve hair quality by reducing androgens. It's important to maintain proper nutrition, including electrolytes and protein, during fasting.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001).

297 upvotes 2 years ago

Sugary beverages increase the risk of pattern hair loss in men by 57%, and type 2 diabetes is linked to female pattern hair loss. Reducing sugar intake and using treatments like finasteride and minoxidil may help manage hair loss.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

484 upvotes 2 years ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Are carbohydrates needed for hair growth

26 upvotes 2 years ago

A 47-year-old male experienced significant hair loss after losing 37 kg in 6 months on a low-carb diet and started taking biotin, zinc, iron, selenium, and spectral dcn-n. Replies suggest that while carbs are not directly needed for hair growth, they help regulate hormones and nutrient absorption, and rapid weight loss can also contribute to hair loss.

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learn Metformin

Can metformin improve scalp health in people with insulin resistance or PCOS? There is no controlled trial showing that metformin improves scalp hair. The PCOS studies most often cited measured unwanted body hair, not scalp density, and a published case report describes hair loss during metformin treatment; any use for hair would be off-label and a decision for a prescribing doctor.

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