research PLCD1 and Pilar Cysts
This study identified a high-risk allele in the PLCD1 gene associated with hereditary trichilemmal cyst formation, proposing a monoallelic two-hit mechanism as the underlying genetic pathogenesis.
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research Monilethrix, a rare inherited hair shaft disorder in siblings
This article discusses the genetic hair disorder monilethrix, characterized by beaded, fragile hair due to defective keratin genes, and reports no effective treatment currently available; variability in severity was noted among affected siblings.
research Eruptive Vellus Hair Cysts: Report of a New Case with Immunohistochemical Study and Literature Review
This case study and literature review describe eruptive vellus hair cysts as uncommon, potentially inherited or acquired lesions, associated with other skin conditions, and challenging to treat despite being benign.
research A Case Report of Kaphaja Granthi w.s.r. to Trichilemmal Cyst
This study described trichilemmal cysts, firm lumps that form from blocked hair follicles, typically found on the scalp but also less commonly on other body parts, affecting less than 10% of the population and possibly inherited as an autosomal dominant trait.
research Promotion of Hair Growth by Applying Sulfur Amino Acids and Other Things to the Skin
In this study, L-methionine and L-serine application was observed to have the most significant effect on hair weight and root length, followed by acetyl L-methionine and L-serine, while glutathione inhibited growth.
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5 / 163 resultscommunity We already know how to permanently fix hair loss. The science is done. The only thing missing is the funding to run one experiment.
A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.
community Female, 30, PCOS diagnosis, MPB Norwood 2. Endo refuses to give anything other than Spironolactone. Feel like I’m at my wit’s end here.
A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.
community Spending $10K on a hair transplant in the U.S. vs $5,000 for one in Turkey
Hair transplants cost more in the U.S. than in Turkey, but quality varies. Proper research is essential, as aggressive transplants can exhaust donor hair, and finasteride only slows hair loss.
community 2nd Year Update FINASTERIDE ONLY from the PHILIPPINEE
A 48-year-old male from the Philippines shared his two-year progress using finasteride only for hair regrowth, experiencing significant improvement without minoxidil. He started with 0.5mg and increased to 1.25mg, later adjusting to every other day due to elevated liver enzymes, and reported 90% hair restoration.
community Genetics are so weird and unpredictable
The user experienced male pattern baldness starting at 18, tried finasteride with no success, and switched to dutasteride, which halted hair loss. Minoxidil had no effect for them, while their brother, who didn't use AR inhibitors, maintained a juvenile hairline and successfully grew a beard with minoxidil, highlighting the unpredictable nature of genetics in hair loss and treatment response.
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