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research Anti-TNF antibody-induced psoriasiform skin lesions in patients with inflammatory bowel disease are characterised by interferon-γ-expressing Th1 cells and IL-17A/IL-22-expressing Th17 cells and respond to anti-IL-12/IL-23 antibody treatment

278 citations , March 2013 in “Gut”

In this study, nearly 5% of anti-TNF-treated patients with IBD developed psoriasiform skin lesions, with smoking identified as a main risk factor, and ustekinumab proved highly effective in severe cases.

research Tyrosine Kinases in Autoimmune and Inflammatory Skin Diseases

88 citations , August 2019 in “Frontiers in immunology”

This review discusses the role of tyrosine kinase signaling pathways in autoimmune and inflammatory skin diseases and reports no new clinical results, highlighting ongoing research into small-molecule tyrosine kinase inhibitors as potential treatments.

research The many faces of interleukin-17 in inflammatory skin diseases

77 citations , April 2016 in “British journal of dermatology/British journal of dermatology, Supplement”

This article reviews the role of IL-17 in inflammatory skin disorders and highlights its potential therapeutic targeting in both neutrophilic and lymphocyte-mediated conditions, reporting no new experimental results.

research The spectrum of inflammatory skin disease following jejuno-ileal bypass for morbid obesity

51 citations , October 1981 in “British Journal of Dermatology”

This study found that in patients who underwent jejuno-ileal bypass for morbid obesity, dapsone was effective in treating inflammatory skin lesions and joint symptoms when other antibiotics failed.

research Selective Ablation of Ctip2/Bcl11b in Epidermal Keratinocytes Triggers Atopic Dermatitis-Like Skin Inflammatory Responses in Adult Mice

40 citations , December 2012 in “PLoS ONE”

This study found that selective deletion of Ctip2 in epidermal keratinocytes in adult mice leads to atopic dermatitis-like inflammation and suggests Ctip2 plays a crucial role in skin barrier maintenance and inflammatory regulation.

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Community Join

5 / 316 results

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Has anyone tried nicotinamide serum for inflammatory hair loss.

3 upvotes 1 year ago

Nicotinamide serum is discussed for its potential benefits in reducing inflammation related to hair loss. One user combines it with minoxidil for hair growth.

community Any chances of my hairloss being inflammatory?

5 upvotes 2 weeks ago

A 20-year-old male has been experiencing hair loss since age 15-16 and is using oral minoxidil, dutasteride, and ketoconazole shampoo, with previous use of oral finasteride and topical minoxidil. He has stabilized hair loss but seeks to rule out inflammatory or immune-related causes, considering a scalp biopsy, and is supplementing with vitamin D3, B12, and iron.

community [26M] Min 5 month progress, worse skin?

49 upvotes 2 years ago

A user experienced skin irritation and acne while using Minoxidil foam, but after stopping both the foam and a sea salt spray, their skin improved. They plan to try oral Minoxidil, suspecting the sea salt spray, not Minoxidil, was the main cause of their skin issues.

community What do people think about using a castor oil pack on thinning hair? It is ant-inflammatory has a lot of vitamins and fatty acids..

4 upvotes 8 years ago

Castor oil is being considered for hair thinning, with some users noting it may prevent hair breakage but not affect DHT-related hair loss. Some users report mixed results, with one mentioning increased body hair growth from oral consumption.

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Learn

9 / 9 results

learn Fluocinolone

Is Fluocinolone a treatment for hair loss itself or just for calming scalp irritation? Fluocinolone acetonide is a prescription corticosteroid approved for inflammatory skin conditions, not for hair loss; no published human trial has measured hair regrowth with it, so at most it may help indirectly by calming an inflamed scalp.

learn Hydrocortisone

Mild corticosteroid used on the skin and scalp

learn Tea tree

How does tea tree oil interact with the scalp environment in products designed for irritation, dandruff, or mild hair shedding? In one 4-week trial, a 5% tea tree oil shampoo reduced mild to moderate dandruff; anti-inflammatory effects have been seen only in lab studies. Tea tree oil itself can irritate the skin or cause allergy.

learn Melatonin

Hormone that regulates sleep, sold as a supplement

learn Lavender

Plant essential oil used in scalp products

learn Azelaic Acid

Acid used in acne and rosacea creams

learn Neem Oil

Oil from the neem tree, used in traditional remedies

learn capsicum

Is capsicum safe for sensitive scalps or inflammatory hair loss? Capsicum may irritate sensitive scalps and worsen inflammatory hair loss.

learn Cetirizine

What makes cetirizine a unique anti-inflammatory option for your scalp? Laboratory work reports that cetirizine lowers PGD2 and other inflammatory mediators, which is why researchers have proposed it for the scalp. There is no approved topical product and the clinical evidence is a few small trials in pattern hair loss (none in inflammatory scalp disease), so scalp use is off-label and experimental.