December 2015 in “Vascular Pharmacology” Different cells affect hair follicle blood vessels, endothelial cells react differently to inflammation and oxidized fats, and prasugrel better protects heart vessels during a procedure than clopidogrel.
28 citations
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April 2024 in “Immunity” In this study, researchers found that hair follicle stem cells activate an immune-modulatory program during wound healing, promoting Treg cell expansion and aiding skin repair, while deleting certain immune components impaired healing and increased inflammation in a mouse model.
70 citations
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June 2023 in “International Journal of Molecular Sciences” In this review, researchers explored how air pollutants increase oxidative stress and inflammation in human skin, affect vitamin D synthesis, and interact with the skin microbiota, also discussing AhR/Nrf2 as a potential target for treating pollution-related skin conditions.
December 2025 in “SKINdeep” This paper reviews existing studies on the role of environmental humidity in skin health, highlighting that low humidity can impair the skin's barrier function and trigger inflammatory responses, though the precise mechanisms remain to be fully explored.
January 2024 in “Skin appendage disorders” This research highlights that various environmental pollutants, including particulate matter, tobacco smoke, and heavy metals, can significantly affect hair follicle health, linking them to conditions like alopecia areata and androgenetic alopecia, underscoring the need for further study in this area.