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research The Wound Reporting in Animal and Human Preclinical Studies (WRAHPS) Guidelines

11 citations , December 2024 in “Wound Repair and Regeneration”

In this study, researchers created the WRAHPS Guidelines to standardize the reporting of preclinical wound healing studies, aiming to improve transparency, enable comparative analysis, and support the development of human clinical trials for wound healing disorders.

research 614 Humanized mouse model for hair follicle studies

September 2019 in “Journal of Investigative Dermatology”

This study established a model using nude mice to successfully graft human scalp skin, maintaining hair follicle growth and skin integrity for at least two months, which may aid preclinical research.

research In-vivo studies to determine Hair Growth Potential of Poly Herbal Medicated Hair Oil in Female Swiss Albino Mice

March 2023 in “Research journal of pharmacy and technology”

This study found that a poly herbal hair oil formulation significantly promoted hair growth in a pre-clinical mouse model.

research 3D-SeboSkin Model for Human ex vivo Studies of Hidradenitis Suppurativa/Acne Inversa

4 citations , June 2021 in “Dermatology”

This study validated the HS 3D-SeboSkin model as a reliable tool for preclinical research, effectively preserving the structure and biomarker expression of lesional and perilesional HS skin ex vivo.

research The Evolution of Emerging Nanovesicle Technologies for Enhanced Delivery of Molecules into and across the Skin

1 citations , February 2024 in “Pharmaceutics”

This review highlights recent developments in nanovesicular carriers for enhancing molecule delivery into and across the skin, focusing on the design and evolution of phospholipid and non-phospholipid systems used in cosmetics and treating various skin conditions.

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5 / 97 results

community Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)

4 upvotes 1 year ago

Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.

community We should actually be hopeful for these recent new developments

112 upvotes 1 year ago

AI advancements, like AlphaFold, are speeding up drug discovery for hair loss, promising more effective treatments. Current options like minoxidil and finasteride have limitations, but new developments could improve solutions in 5-10 years.

community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

29 upvotes 2 months ago

Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

community Amplifica: Hope or Cope? A Review of Their Pipeline

9 upvotes 4 weeks ago

Amplifica's AMP-303 showed a modest increase in hair growth, but results were inconsistent and potentially misleading. Hyaluronic acid and osteopontin are being explored for hair growth, with varying effects on different hair types and conditions.

community Why you can still look forward to PP405 and JXL-069

22 upvotes 1 month ago

PP405 and JXL-069 are the same compound, but users experienced no results due to flawed application methods. The topical gel formulation of PP405 is designed to target hair follicle stem cells effectively, unlike liquid solutions that fail to penetrate deeply.

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