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research Extracts for the Hair Growth Stimulation using In vivo and In vitro Test Models

January 2002 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology”

This study found that several natural extracts, including Prunus mume and Rubi Fructus, showed hair growth-promoting effects in mice, but none significantly impacted human hair dermal papilla cells in vitro.

research The In Vivo and In Vitro Effects of Terminalia bellirica (Gaertn.) Roxb. Fruit Extract on Testosterone-Induced Hair Loss

July 2023 in “Journal of Microbiology and Biotechnology”

This study found that oral administration of Terminalia bellirica enhanced hair growth in testosterone-suppressed conditions in both human cell and mouse models, outperforming finasteride, a current commercial hair loss treatment.

research A comparative in vivo and in vitro evaluation of hair growth potential of extracts and an isolate from petroleum ether extract of Cuscuta reflexa Roxb

7 citations , September 2014 in “Beni-Suef University Journal of Basic and Applied Sciences”

This study found that ethanolic and petroleum ether extracts of Cuscuta reflexa, as well as an isolate from these extracts, improved hair growth and follicle characteristics in androgen-induced alopecia in rats.

research Formulation and In-vivo Assessment of Topical Polyherbal Hair Serum to Promote Hair Growth

December 2023 in “International journal of drug delivery technology”

In this study, researchers developed a polyherbal serum using extracts from various herbs and tested it on rats with testosterone-induced alopecia, observing it potentially promotes hair growth and decreases androgen-induced hair loss, with results compared to a positive control using finasteride.

research Jagged1 and Epidermal Growth Factor Promoted Androgen-Suppressed Mouse Hair Growth In Vitro and In Vivo

7 citations , January 2020 in “Frontiers in Pharmacology”

This study found that the combination of epidermal growth factor and Jagged1 significantly stimulated hair growth in mice with androgen-suppressed conditions, suggesting potential therapeutic implications for androgenetic alopecia.

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community Rubedo Life Sciences Announces Clinical Study to Treat Hair Loss with GPX4 Modulator RLS-1496, First Human Ex Vivo Evidence Demonstrates Robust Hair Follicle Growth

1071 upvotes 1 week ago

Rubedo Life Sciences is developing a GPX4 modulator, RLS-1496, for hair loss treatment, showing promising hair follicle growth in early tests. Concerns include potential side effects like organ damage, with a realistic market release several years away.

community mangifera indica (mango oil) inhibits dkk1, dht TYPE 2 and activate wnt signal in vivo

6 upvotes 3 years ago

Mango oil may inhibit DKK1 and DHT, potentially aiding hair growth by activating the Wnt signaling pathway. A user plans to test mango leaves juice and other Ayurvedic products for hair regrowth.

community new way to activate stem cells to make hair grow

42 upvotes 7 years ago

Stem cell-related treatments and drugs like RCGD423 and WAY are being tested for hair growth. Clinics are conducting tests on patients who haven't had previous treatments.

community Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)

4 upvotes 1 year ago

Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

211 upvotes 1 year ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

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learn KY19382

Experimental compound that activates hair-growth signals, tested only in animals

learn Stem Cell Factor

learn Neem Oil

Oil from the neem tree, used in traditional remedies

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