This study observed that, among alopecia areata patients in Fujian, China, lower IgG4 levels and higher IFN-γ levels were statistically significant, suggesting their potential role as biomarkers for the condition and highlighting avenues for future therapeutic developments.
66 citations
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April 1995 in “The journal of cell biology/The Journal of cell biology” In this study, researchers reported that a keratinocyte growth factor-Ig fusion protein could specifically detect and localize KGFRs in epithelial tissues, suggesting a method for histochemical detection of growth factor receptors.
3 citations
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May 2019 in “Australasian Journal of Dermatology” This letter to the editors discusses the nature of alopecia in Cronkhite–Canada syndrome and questions whether it is truly telogen effluvium, but it reports no new clinical findings.
January 2026 in “Journal of Cutaneous Immunology and Allergy” In this case report, a young Japanese man was diagnosed with scalp IgG4-related disease, which mimicked acne keloidalis nuchae but was identified by histopathology and elevated serum IgG4 levels as a systemic fibroinflammatory disorder, highlighting the importance of differential diagnosis in atypical scarring alopecia.
148 citations
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December 2018 in “Journal of autoimmunity” This review discusses genetic and environmental factors contributing to autoimmunity in alopecia areata and reports no new clinical findings, emphasizing the need for further study on its aetiology and pathophysiology.