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GlossaryImmunodeficient Mice

laboratory mice with weakened or absent immune systems

Immunodeficient mice, also known as immunocompromised mice, are laboratory mice that have a weakened or entirely absent immune system. This makes them valuable for scientific research, particularly in studying human diseases, cancer, and testing new treatments, as they can accept human cells and tissues without rejecting them.

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research Dissociated Skin Cells Regenerate Hair Follicles in a Microwound: The Punch Assay

5 citations , July 2018 in “Experimental Dermatology”

The "Punch Assay" can regenerate hair follicles efficiently in mice and has potential for human hair regeneration.

research Mouse Models for the Study of Human Hair Loss

36 citations , October 1996 in “Dermatologic Clinics”

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.

research Experimental Induction of Alopecia Areata-Like Hair Loss in C3H/HeJ Mice Using Full-Thickness Skin Grafts

131 citations , November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

research Transplants from Balding and Hairy Androgenetic Alopecia Scalp Regrow Hair Comparably Well on Immunodeficient Mice

17 citations , May 2003 in “Journal of The American Academy of Dermatology”

Hair from balding and non-balding areas regrows similarly on mice.

research Sebaceous Gland Regeneration in Human Skin Xenografts

9 citations , May 2010 in “Journal of Investigative Dermatology”

Human sebaceous glands can grow back in skin grafts on mice and work like normal human glands.

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community All of us when Tsuji hair cloning releases and becomes affordable

in Treatment 126 upvotes 5 years ago

People are discussing hair loss treatments and expressing hope for future hair cloning. Some mention using Minoxidil, finasteride, and RU58841.

community Pyrilutamide cease and desist from Kintor

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Considering a hair transplant, using Pyrilutamide, the potential availability of CosmeRNA, and the significance of taking Minoxidil and Finasteride for long-term results.

community Dht kills hair, but no one says why?

in Finasteride/Dutasteride 40 upvotes 6 months ago

DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

community My Theory Of Androgenic Alopecia

in Research/Science 19 upvotes 3 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community Medications that cause extra hair growth

in Research/Science 123 upvotes 2 years ago

The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.