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GlossaryImmunodeficient Mice

laboratory mice with weakened or absent immune systems

Immunodeficient mice, also known as immunocompromised mice, are laboratory mice that have a weakened or entirely absent immune system. This makes them valuable for scientific research, particularly in studying human diseases, cancer, and testing new treatments, as they can accept human cells and tissues without rejecting them.

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research Mouse Models for the Study of Human Hair Loss

36 citations, October 1996 in “Dermatologic Clinics”

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.

research Transplants from Balding and Hairy Androgenetic Alopecia Scalp Regrow Hair Comparably Well on Immunodeficient Mice

17 citations, May 2003 in “Journal of The American Academy of Dermatology”

Hair from balding and non-balding areas regrows similarly on mice.

research Dissociated Skin Cells Regenerate Hair Follicles in a Microwound: The Punch Assay

5 citations, July 2018 in “Experimental Dermatology”

The "Punch Assay" can regenerate hair follicles efficiently in mice and has potential for human hair regeneration.

research Effects of Adipose-Derived Stem Cells and Platelet-Rich Plasma for Prevention of Alopecia and Other Skin Complications of Radiotherapy

6 citations, November 2020 in “Annals of Plastic Surgery”

Adipose-derived stem cells and platelet-rich plasma together can protect skin and hair from radiotherapy damage.

research Wound-Healing Effects of Frozen-Thawed Allogeneic Fibroblast Sheet Transplantation and Xenogeneic Fibroblast Cell Sheet Transplantation Cultured on a New Substrate

March 2025 in “Tissue and Cell”

Frozen-thawed fibroblast sheets enhance wound healing and hair growth in mice.

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in Research/Science 123 upvotes 1 year ago

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