Search
for

    Research

    5 / 1000+ results

      research Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing

      176 citations , August 2015 in “ˆThe ‰journal of allergy and clinical immunology/Journal of allergy and clinical immunology/˜The œjournal of allergy and clinical immunology”
      This study identified a distinct cytokine activation signature in alopecia areata, involving TH2, TH1, IL-23, and IL-9/TH9 pathways, suggesting potential targeting strategies similar to those in psoriasis and atopic dermatitis.

      research The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside

      144 citations , November 2020 in “Frontiers in immunology”
      This study summarizes how the IL-23/IL-17 axis contributes to inflammatory skin diseases like psoriasis and highlights that biologics targeting this pathway, including monoclonal antibodies against IL-23 and IL-17, have shown efficacy in clinical trials for these conditions.

      research IL-12/IL-23 neutralization is ineffective for alopecia areata in mice and humans

      20 citations , December 2019 in “ˆThe ‰journal of allergy and clinical immunology/Journal of allergy and clinical immunology/˜The œjournal of allergy and clinical immunology”
      In this study, ustekinumab did not promote hair regrowth in human patients with alopecia areata or prevent disease development in an AA mouse model, suggesting limited efficacy for this treatment.

      research Off-label dermatologic uses of IL-23 inhibitors

      2 citations , December 2024 in “Journal of Dermatological Treatment”
      This review suggests that IL-23 inhibitors may be effective for various non-psoriatic inflammatory skin conditions, but emphasizes the need for further large-scale trials to confirm their efficacy and safety.
    View more "il-23" in research →

    Learn

    1 / 1 results

    Community Join

    5 / 123 results

      community My dermatologist won’t prescribe me Fin

       79 upvotes 1 year ago
      A 23-year-old Italian man in Switzerland is experiencing hair loss and cannot get a prescription for Finasteride, only Minoxidil. He seeks advice on obtaining Finasteride through online pharmacies or by consulting different doctors.

      community 4 months!! We making progress!!

       506 upvotes 1 year ago
      A user shared their successful hair regrowth journey using 0.5 mg Dutasteride, 2.5 mg oral Minoxidil, and Biotin gummies, after switching from Finasteride due to insomnia. They highlighted the importance of brushing the scalp for blood flow and reported significant progress in four months without side effects.

      community Failed HT or expected result? 4505 grafts, Eugenix, New Delhi.

      in Transplants  36 upvotes 1 year ago
      The hair transplant at Eugenix in New Delhi resulted in poor density and texture, with only about 2,500 grafts surviving out of 4,500. The user is considering holding the clinic accountable and exploring options like shaving, using hair fibers, or seeking another transplant.
    View more "il-23" in community →

    Experts

    1 / 20 results

    Clinics

    2 / 13 results