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    GlossaryInterleukin-23 (IL-23)

    protein that promotes inflammation and regulates immune responses

    Interleukin-23 (IL-23) is a type of cytokine, which is a protein that plays a crucial role in the immune system by promoting inflammation and helping to regulate the body's defense against infections. It is particularly important in the development and maintenance of certain autoimmune diseases, such as psoriasis and inflammatory bowel disease, by influencing the activity of specific immune cells called T-helper 17 (Th17) cells.

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      community Hair Loss “Cure” for Inflammation: Topical Roflumilast

      in Research/Science  32 upvotes 2 months ago
      Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

      community 8 years of hair loss, turning 30 next month

      in Progress Pictures  154 upvotes 8 months ago
      The user has been dealing with hair loss for 10 years, worsened by psoriasis, and uses minoxidil and finasteride. They seek advice on managing psoriasis and hair loss, with suggestions to see a dermatologist, try different shampoos, and be patient.

      community HLT Megathread on HMI-115 (key takeaways in comments)

      in Research/Science  39 upvotes 3 years ago
      HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

      community Shed 2 years into finasteride and minoxidil

      in Minoxidil  8 upvotes 1 year ago
      A user has been on finasteride for 1.5 years and minoxidil for 2 years, experiencing worsening hair shedding, losing 300+ hairs per wash. They are concerned if this indicates the medicine isn't working and are seeking others' experiences.

      community My dermatologist won’t prescribe me Fin

      in Treatment  81 upvotes 6 months ago
      A 23-year-old Italian man in Switzerland is experiencing hair loss and cannot get a prescription for Finasteride, only Minoxidil. He seeks advice on obtaining Finasteride through online pharmacies or by consulting different doctors.