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GlossaryHenoch-Schönlein purpura (IgA vasculitis)

condition causing small blood vessel inflammation and purplish skin rash

Henoch-Schönlein purpura (HSP), also known as IgA vasculitis, is a condition that causes inflammation and bleeding in the small blood vessels, primarily affecting the skin, joints, intestines, and kidneys. It is characterized by a distinctive purplish rash, often on the lower legs and buttocks, abdominal pain, and joint inflammation. The exact cause is unknown, but it often follows an upper respiratory infection and involves the deposition of IgA immune complexes in the affected tissues.

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research Involvement of Mast Cells and CB1 in the Pathogenesis of IgA Vasculitis

April 2023 in “Journal of Investigative Dermatology”

Mast cells and the CB1 receptor may be key in causing IgA vasculitis.

research Skin Biopsy

106 citations, December 2015 in “Journal of The American Academy of Dermatology”

Correct skin biopsy techniques are crucial to avoid misdiagnosis of skin diseases.

research Colchicine in Managing Skin Conditions: A Systematic Review

21 citations, January 2022 in “Pharmaceutics”

Colchicine might help treat different skin diseases, but more research is needed to confirm its effectiveness and safe dosage.

research Skin Manifestations Associated With Systemic Diseases – Part I

11 citations, September 2021 in “Anais Brasileiros de Dermatologia”

The conclusion is that early diagnosis of skin signs linked to diseases like Lupus, Dermatomyositis, and Rheumatoid Arthritis is crucial to prevent serious complications.

research Dermoscopy of Discoid Lupus Erythematosus: Report of Two Cases

13 citations, July 2014 in “The Journal of Dermatology”

Dermoscopy helped diagnose discoid lupus erythematosus in two patients without needing skin biopsies.

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