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Research

5 / 1000+ results

research Next generation human skin constructs as advanced tools for drug development

69 citations , June 2017 in “Experimental Biology and Medicine”

This review discusses the advancements and challenges in developing in vitro human skin models incorporating components like vasculature for drug testing and disease research, but reports no new clinical results.

research 685 Modelling intrinsic and extrinsic cellular senescence in vitro with complex bioengineered human skin constructs

July 2024 in “Journal of Investigative Dermatology”

Bioengineered skin models aging well, useful for studying aging and testing treatments.

research Research Progress on Construction Technology of 3D Human Skin Models and Its Application Prospects in Dermatology

February 2026 in “International Journal of Molecular Sciences”

This paper reviews advancements in 3D human skin models using bioprinting, organoid, and organ-on-a-chip technologies, noting improvements in physiological realism through vascularization and multi-omics data, but also highlighting challenges such as cost and lack of standardization that hinder clinical adoption.

research An improved and rapid method to construct skin equivalents from human hair follicles and fibroblasts

48 citations , August 2001 in “Experimental dermatology”

This study developed a rapid, cost-effective three-dimensional skin equivalent model using human dermal fibroblasts, collagen, and hair follicles, which closely resembles natural human skin and can be used for autologous transplantation.

research Tissue-engineered dermal substitutes constructed by human embryonic stem cell-derived fibroblasts facilitate the repair of skin wounds

March 2026 in “Frontiers in Bioengineering and Biotechnology”

In this study, researchers demonstrated that fibroblasts derived from human embryonic stem cells can be used to create tissue-engineered dermal substitutes, effectively repairing mouse skin wounds within 20 days, highlighting a promising method for clinical applications in skin repair.

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Community Join

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community A stress hormone has been found to signal through skin cells to repress the activation of hair-follicle stem cells in mice

30 upvotes 5 years ago

Stress can lead to hair loss by affecting hair-follicle stem cells, and this loss is harder to recover from if one has male pattern baldness (MPB). Treatments like finasteride and minoxidil are used to address hair loss, but stress-related hair loss differs from androgenic alopecia.

community Dht kills hair, but no one says why?

in Finasteride/Dutasteride 40 upvotes 1 year ago

DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

community Best science-backed supplements for androgenetic alopecia? Looking for real evidence

7 months ago

The conversation discusses treatments for androgenetic alopecia, focusing on evidence-based supplements to complement finasteride. Suggestions include oral minoxidil, saw palmetto, pumpkin seed oil, tocotrienols, and various other supplements, while emphasizing the importance of scientific backing and cautioning against saw palmetto if already using finasteride.

community The Real Reason For Hair Loss?

9 months ago

Hair loss is linked to scalp fibrosis and tension, which result from chronic mechanical stress and androgenic signaling. Treatments include blocking androgens with finasteride, promoting hair growth with topical minoxidil, and improving scalp mobility through exercises.

community Occipitalis Muscle Tension Theory

13 upvotes 7 months ago

Scalp tension from the occipitalis muscle is theorized to contribute to hair loss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.

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Clinics

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All 13 clinic results →

Learn

9 / 800 results

learn Osteopontin

What does osteopontin do in skin healing and inflammation? Osteopontin takes part in wound repair in mouse skin; its role in human scalp healing and inflammation has not been studied.

learn Vitamin C

Is topical Vitamin C effective for scalp and hair growth? No human trial has shown that topical vitamin C improves hair growth or scalp health. Its skin trials were on other body sites, and the hair data come from laboratory studies.

learn retinol

Can retinol help enhance the absorption of ingredients like minoxidil or peptides? No human study has measured whether retinol increases scalp absorption of minoxidil or peptides. Retinoids thicken rather than thin the epidermis, and they can irritate skin and need caution in pregnancy.

learn GHK-Cu

Copper peptide used in skin and hair cosmetics

learn Linoleic Acid

Does linoleic acid reduce scalp irritation that can worsen hair loss? Linoleic acid is part of the skin barrier, but no human study shows that applying it reduces scalp irritation or slows hair loss.

learn Vitamin D

Vitamin made in the skin from sunlight, also taken as a supplement

learn Fluocinolone

Can long-term use of Fluocinolone affect the health of hair follicles? There is no long-term human trial measuring what topical fluocinolone does to hair follicles; what is documented is the label's warning about skin atrophy with prolonged use, plus a 2007 mouse study suggesting hair-follicle bulge stem cells do not repair steroid-induced atrophy.

learn Peppermint

herb and oil thought to stimulate skin and hair

learn Dexpanthenol

Provitamin B5, a moisturiser in hair and skin products

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Experts

1 / 3 results

SMP Specialist
Noelle Skin
Nice, France

Noelle Skin