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research Ultrastructural Localization of Hair Keratins in Human Scalp Hair Shafts as Revealed by Rapid-Freezing Immunocytochemistry.

3 citations , January 1998 in “ACTA HISTOCHEMICA ET CYTOCHEMICA”

This study used rapid-freezing immunocytochemistry to successfully map the ultrastructural localization of hair keratins in human scalp hair, primarily finding them in macrofibrils in the cortex and endocuticle.

research Distribution of bacterial community structures on human scalp hair shaft in relation to scalp sites

September 2023 in “Bioscience, biotechnology, and biochemistry”

In this study, researchers observed that bacterial community structures on human scalp hair are unique to individuals and show consistent patterns across different sampling sites on the scalp, without significant variation between these sites.

research Ultrastructural Localization of S100A3, a Cysteine-rich, Calcium Binding Protein, in Human Scalp Hair Shafts Revealed by Rapid-freezing Immunocytochemistry

40 citations , April 1999 in “Journal of Histochemistry & Cytochemistry”

In this study, the researchers identified the specific subcellular localization of the protein S100A3 in the endocuticle and cortex of human hair shafts.

research Evidence for various calcium sites in human hair shaft revealed by sub-micrometer X-ray fluorescence

31 citations , December 2002 in “Biochimica et biophysica acta. G, General subjects/Biochimica et biophysica acta. General subjects (Online)”

This study identified two types of calcium in human scalp hair, with one type highly variable between individuals, potentially impacting the analysis of environmental and medical factors related to hair calcium.

research Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression

128 citations , March 2006 in “American Journal of Pathology”

The study found that prolactin expressed in human scalp hair follicles acts as an autocrine modulator, inhibiting hair growth and promoting hair follicle regression, which may contribute to hair loss in hyper-prolactinemia patients.

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Community Join

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community Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)

4 upvotes 1 year ago

Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.

community Now that hair loss in mice is solved, can they move on to people?

709 upvotes 6 months ago

Hair loss treatments are being tested on mice, with methods like minoxidil and stem cell therapy showing promising results. However, human trials are still years away, leading to humorous frustration about mice benefiting first.

community Regrowth with only Nizoral and Lifestyle Changes; focusing on scalp health & nervous system

89 upvotes 8 months ago

The user reported subtle hair regrowth by focusing on scalp health and lifestyle changes, using Nizoral shampoo and methods to reduce inflammation and cortisol, without using finasteride, minoxidil, or other common treatments. Opinions in the conversation varied, with some skeptical of the results and others acknowledging the potential benefits of addressing scalp health and inflammation.

community Prevention of age-related beard graying in humans by the topical application of Eriodictyon angustifolium extract

5 upvotes 4 years ago

Topical application of Eriodictyon angustifolium extract can prevent and reverse age-related beard graying and darken gray hair by increasing melanin production. Sterubin, a component of the extract, also promotes hair pigmentation and protects cells from DNA damage.

community It's always the Mice that gets to grow back hair.

434 upvotes 11 months ago

Sodium dodecyl sulfate, oleic acid, and palmitoleic acid may promote hair growth, but their safety and effectiveness for humans are uncertain. Users consider trying these treatments cautiously, exploring alternatives like ostrich oil and microneedling.

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Learn

9 / 34 results

learn oleic acid

How does Oleic Acid support hair follicle strength and growth? Lab and animal studies suggest oleic acid may help the scalp barrier and hair shaft. No human trial shows that it strengthens follicles or slows hair loss.

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Castor oil

Thick plant oil used in hair care

learn Exosomes

Tiny cell-derived particles offered by clinics as an injectable treatment

learn Neem Oil

Oil from the neem tree, used in traditional remedies

learn Follistatin

Protein that blocks activin, a growth-regulating signal

learn Vitamin C

Is topical Vitamin C effective for scalp and hair growth? No human trial has shown that topical vitamin C improves hair growth or scalp health. Its skin trials were on other body sites, and the hair data come from laboratory studies.

learn Vitis vinifera

Can grape extract help with scalp circulation or hair growth? There is no human evidence that grape extract improves scalp blood flow or hair growth; the related data are on blood pressure and in mice.

learn Ginkgo biloba

Does ginkgo biloba improve scalp circulation, and does that help hair regrowth? No human study has shown that ginkgo improves scalp circulation or regrows hair; the direct hair evidence is a 1993 mouse study. Ginkgo may increase bleeding risk, especially with blood thinners.
Can ginkgo biloba reduce scalp inflammation that contributes to hair loss? There is no human evidence that ginkgo reduces scalp inflammation or helps hair loss. Ginkgo may increase bleeding risk and interact with medicines, so talk to a doctor or pharmacist first.

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Clinics

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All 12 clinic results →

Experts

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Trichologist
Kirsten J. Scalp
Greenville, SC, United States

Kirsten J. Scalp