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research Clinical and phototrichogrammatic evaluation of estradiol replacement therapy on hair growth in postmenopausal Japanese women with female pattern hair loss: a pilot study

November 2023 in “International Journal of Women's Dermatology”

In this study, female patients undergoing hormone replacement therapy showed improvements in frontal hairline appearance and increased hair plucking strength, suggesting positive effects of estradiol on hair growth while excluding age-related factors.

research MON-203 Dermatological Effects Of Hormone Replacement Therapy

October 2025 in “Journal of the Endocrine Society”

This research review observed that topical hormone replacement therapy, particularly estradiol and estradiol-testosterone combinations, significantly increased Type I and III collagen synthesis in the skin of postmenopausal women, suggesting benefits against collagen loss-related skin aging effects such as reduced elasticity and increased dryness.

research SUN-144 Initiating Estradiol Hormone Therapy in a Transgender Woman With Multifocal Idiopathic Localization-Related Epilepsy

October 2025 in “Journal of the Endocrine Society”

In this case report, a transgender woman with refractory epilepsy began estrogen therapy for gender-affirming purposes, experiencing stable epilepsy and reduced gender dysphoria through ongoing multidisciplinary care, highlighting the importance of careful management for similar patients.

research Sex hormones and related compounds, including hormonal contraceptives

January 2014 in “Side effects of drugs annual”

This review discusses the 2011 publications on the side effects of sex hormones and related compounds, without reporting new clinical results.

research Ultra-low dose estradiol and dydrogesterone for the treatment of menopausal symptoms in a pooled, multi-ethnic population

5 citations , September 2024 in “Maturitas”

In this study, an ultra-low dose combination of estradiol and dydrogesterone significantly reduced hot flushes and improved health-related quality of life among a multi-ethnic population of postmenopausal women, with no notable difference in serious adverse events compared to placebo.

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community Taking HRT medication not only cured my thinning hair, it gave me better hair than I ever had before

in Transgender 12 upvotes 10 months ago

Hormone replacement therapy with spironolactone and estradiol significantly improved hair thickness and growth, surpassing previous treatments like dutasteride, finasteride, and minoxidil. The user experienced regrowth in receded areas and a more youthful appearance.

community HRT temple regrowth - 0 months, 3 months, 6 months

22 upvotes 2 months ago

The conversation is about hair regrowth progress using hormone replacement therapy (HRT) with Estradiol and Cyproterone, without using Minoxidil. The user shares progress pictures over 0, 3, and 6 months.

community Experiences of regrowth on HRT

14 upvotes 2 weeks ago

A 23-year-old is experiencing hair loss and is using a regimen including topical Minoxidil, finasteride, spironolactone, and Estradiol gel as part of hormone replacement therapy (HRT). They are hopeful for hair regrowth and are considering using a micro needler, with others suggesting that their current treatment could lead to significant improvement.

community progress pics (HRT, fin, min, microneedling) (35, trans non-binary)

11 upvotes 1 year ago

A non-binary transfeminine person experienced significant hair regrowth after starting finasteride, minoxidil, microneedling, and hormone replacement therapy with estradiol. They encourage trans individuals concerned about hair loss to consider estrogen as it has greatly improved their hair condition.

community Regrowth after 9 months of DHT blockers, and 6 months of HRT

in Transgender 24 upvotes 10 months ago

A 20-year-old saw significant hair regrowth after 9 months of using DHT blockers (finasteride and dutasteride) and 6 months of hormone replacement therapy (HRT) with estradiol. The regrowth is attributed to low testosterone and high estradiol levels, without using Minoxidil.

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