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      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

      learn Clascoterone

      a novel topical treatment that inhibits DHT on androgen receptors

      learn Tofacitinib

      a JAK inhibitor for alopecia areata and other autoimmune conditions

      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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      community Can HMI-115 reverse miniaturization?

      in Research/Science  12 upvotes 3 years ago
      HMI-115, a potential treatment for hair loss that can reverse miniaturization and make individual hairs thicker, as evidenced by data from macaques given the treatment and one subject in the phase I trial.

      community 22 years since the last major development

      in Technology  49 upvotes 4 years ago
      The conversation discusses the lack of significant advancements in hair loss treatments since the introduction of finasteride 22 years ago, with many expressing frustration over the failure of new projects and skepticism about future developments. Some users mention hair transplants and other potential alternatives like Alfatradiol and Fluridil, but acknowledge finasteride's dominance in the market due to its effectiveness and affordability.