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GlossaryHistopathology (Histological Analysis)

study of diseased tissues under a microscope

Histopathology, also known as histological pathology, is the study of diseased tissues under a microscope. It involves examining tissue samples to identify abnormalities, such as cancerous cells or signs of inflammation, which can help diagnose various medical conditions. This detailed analysis is crucial for understanding the underlying pathology of diseases and guiding appropriate treatment plans.

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research Transcriptome Analysis of Skin from SMP30/GNL Knockout Mice Reveals the Effect of Ascorbic Acid Deficiency on Skin and Hair

5 citations, June 2017 in “in Vivo”

Vitamin C deficiency changes gene expression, affecting skin and hair health.

research Differential Stripping: Determination of the Amount of Topically Applied Substances Penetrated into the Hair Follicles

162 citations, August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

research Improved Fetal Hair Follicle Development by Maternal Supplement of Selenium at Nano Size (Nano-Se)

18 citations, September 2011 in “Livestock science”

Maternal Nano-Se supplements improve fetal hair follicle development in cashmere goats.

research Caizhixuan Hair Tonic Regulates Both Apoptosis and the PI3K/Akt Pathway to Treat Androgenetic Alopecia

February 2023 in “PLOS ONE”

Caizhixuan hair tonic helps treat hair loss by promoting hair growth and improving hair follicles.

research Mutations in the Helix Termination Motif of Mouse Type I IRS Keratin Genes Impair the Assembly of Keratin Intermediate Filament

27 citations, November 2007 in “Genomics”

Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.

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community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 6 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community microneedle, any long term users damage?

mishaog in Microneedling 35 upvotes 8 months ago

Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.

community One year of progress (Fin, 1mg)

m00tzman in Is this regrowth? 281 upvotes 1 month ago

The user started finasteride (1mg) a year ago for hair thinning, experiencing stabilization but not significant regrowth. Suggestions included adding minoxidil, microneedling, and considering a hair transplant for improved results.

community DUPA/Retrograde might not be DHT based...GET A BIOPSY QUICK or permanent Hair Loss!

noeyys in Research/Science 34 upvotes 2 days ago

DUPA and retrograde alopecia may not be solely DHT-based, and a biopsy is crucial for accurate diagnosis and treatment. Treatments mentioned include dutasteride, oral minoxidil, pioglitazone, clobetasol, calcipotriol, ketoconazole, and doxycycline, depending on the specific condition.

community Verteporfin update - donor hair regeneration human trial

Synizs in Research/Science 22 upvotes 2 years ago

A human trial of verteporfin, a potential treatment for hair loss, with some users noting potential improvements in scarring and overall healing compared to control areas.

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