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research Dramatic Clinical Improvement With Biotin Mega‐Dose Therapy in a Neonate With Holocarboxylase Synthetase Deficiency

2 citations , August 2024 in “Molecular Genetics & Genomic Medicine”

In this case study, an 8-day-old neonate with holocarboxylase synthetase deficiency showed dramatic improvement in lactic acidosis and overall clinical condition following biotin mega-dose therapy, highlighting the importance of early genetic testing and timely treatment in such metabolic disorders.

research Abstract #1182315: Biotin and thyroid function test

May 2022 in “Endocrine practice”

This case report illustrates that high-dose biotin supplementation can cause false thyroid function test abnormalities in vitro, emphasizing the need to assess biotin intake before testing.

research EVALUATION OF THE EFFICACY AND TOLERABILITY OF BIOTIN IN THE COMPLEX TREATMENT OF ANDROGENIC ALOPECIA

August 2026 in “Bulletin of the Medical Institute of Continuing Education”

This observational study found that a high-dose biotin regimen of 10,000 mcg/day reduced hair loss and improved hair and scalp conditions in female patients with androgenic alopecia, with effects lasting beyond treatment discontinuation, warranting further investigation into biotin's role in combination therapy.

research A Randomized Double-Blind Evaluation of a Novel Biotin and Silicon Ingredient Complex on the Hair and Skin of Healthy Women

January 2021 in “Journal of clinical & experimental dermatology research”

This study found that a high dose of LustrivaTM, containing biotin and silicon, significantly increased hair thickness and reduced facial wrinkle depth in women with thinning hair compared to a placebo, without any reported adverse events.

research Analytical interference of biotin

January 2020

This review highlights the potential analytic interference of high-dose biotin with immunochemical tests, which may lead to diagnostic errors and suggests pausing biotin consumption before laboratory testing.

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community 20M – Started Fin + Minox + High Dose D3 a month ago, already seeing baby hairs everywhere

5 upvotes 8 months ago

A 20-year-old started using finasteride, topical minoxidil, and high-dose Vitamin D3 a month ago and is already seeing new hair growth. Others suggest adding dermastamping for better results.

community Around 2 months oral Fin/min low dose

80 upvotes 1 year ago

The user experienced significant hair regrowth after two months on a Hims oral treatment combining 3 mg minoxidil, 1.1 mg finasteride, and vitamins. The treatment is considered a normal/high dose, and the user reported initial side effects like oily skin and acne, which subsided over time.

community Bryan Johnson and his Hair routine, what's the point?

in Hair Systems 24 upvotes 5 months ago

Dutasteride and high-dose Minoxidil are the primary treatments maintaining hair, with additional supplements and therapies like red light offering minimal extra benefit. The discussion criticizes promoting expensive hair care products when basic medications are doing most of the work.

community 18m 2.5 mg dut + topical min + 5 mg injectable ghk-cu progress. caught agressive loss early seemingly. may i have a few more years of handsomeness upon me.

in Is this regrowth? 24 upvotes 1 year ago

An 18-year-old is using a high-dose treatment for hair loss, including 2.5 mg dutasteride, topical minoxidil, and injectable GHK-Cu, despite minimal hair loss. Many users suggest reducing the dutasteride dose due to potential side effects and recommend starting with finasteride instead.

community Four months on dutasteride/minoxidil oral

68 upvotes 2 weeks ago

A 44-year-old has been using a combination of oral dutasteride (0.5mg), minoxidil (2.5mg), and biotin (10mg) daily for four months, noticing hair regrowth with some concern about side effects like numbness. Another user increased their dutasteride dose from 0.5mg to 1mg, reporting significant hair growth without side effects.

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learn Biotin

How much biotin is too much biotin? The NIH Adequate Intake for adults is 30 mcg of biotin a day, and supplements often contain hundreds of times that; no toxic dose has been identified, but the FDA warns that high-dose biotin can distort blood tests including troponin, so tell your doctor and the lab before any test.