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      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn RU58841

      a potent but unapproved and potentially problematic topical anti-androgen

      learn Castor oil

      a traditional, natural remedy touted for promoting scalp health and hair growth

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      community IGE Hair Loss and Miniaturization

      in Chat  3 upvotes 6 months ago
      A 23-year-old male is experiencing diffuse hair loss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.

      community No idea what's causing my hair thinning

      in Chat  2 upvotes 11 months ago
      The user is experiencing diffuse hair thinning despite using finasteride and oral minoxidil, with no hairline recession or bald spots. Suggestions include checking for telogen effluvium, considering a JAK inhibitor for potential autoimmune issues, and conducting further tests to rule out other causes.

      community New 2025 study: high dose oral minoxidil (up to 10mg)

      in Research/Science  80 upvotes 2 weeks ago
      High-dose oral minoxidil (>5 mg/day) can increase hair density in some men with androgenetic alopecia, but side effects like extra body hair and heart issues are common. Gradual dose increase is advised, but adverse effects may lead to discontinuation or dose adjustments.

      community High blood pressure issue with Dr?

      in General  93 upvotes 1 month ago
      A 48-year-old male is experiencing hair loss despite taking finasteride for four months. He is considering oral minoxidil but is concerned about high blood pressure and is unsure about taking spironolactone.