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research Effects of In Vivo-Administered 2,3,7,8-Tetrachlorodibenzo-p-dioxin on Receptor Binding of Epidermal Growth Factor in the Hepatic Plasma Membrane of Rat, Guinea Pig, Mouse, and Hamster

164 citations , December 1984 in “Proceedings of the National Academy of Sciences”

TCDD reduces EGF receptor activity and causes various developmental changes in animals.

research 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Causes an Increase in Protein Kinases Growth Hepatic Associated with Epidermal Factor Receptor in the Plasma Membrane

60 citations , December 1988 in “Journal of Biochemical Toxicology”

TCDD reduces EGF receptors in the liver, affecting growth and development.

research Potential Role and Therapeutic Interests of Myo-Inositol in Metabolic Diseases

369 citations , June 2013 in “Biochimie”

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

research Extracellular Vesicles as Surrogates for Drug Metabolism and Clearance: Promise vs. Reality

7 citations , August 2023 in “Life”

Extracellular vesicles could help tailor drug treatments, but more research is needed.

research Membrane Androgen Receptors May Mediate Androgen Reinforcement

37 citations , February 2010 in “Psychoneuroendocrinology”

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

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community Oral Minoxidil and Grapefruit Juice

in Research/Science 96 upvotes 2 years ago

The conversation is about the potential dangers of taking oral minoxidil and grapefruit juice together. Some users express concern about dangerous drug interactions, while others argue that grapefruit juice may inhibit the metabolism of finasteride. The conclusion is that grapefruit juice may make finasteride less effective, but it won't affect minoxidil.

community how does my progress look 18M 3 months on fin 1mg daily

in Progress Pictures 277 upvotes 2 years ago

An 18-year-old male's successful hair regrowth after three months of using finasteride 1mg daily. He reported no side effects and other users expressed admiration and curiosity about his results.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 6 months ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community Switching to Oral from Topical min effective or not

in Minoxidil 6 upvotes 8 months ago

Switching from topical to oral minoxidil may lead to better results for some users, with oral minoxidil generally being more effective due to higher absorption. However, it can also cause side effects like hypertrichosis and blood pressure issues, and individual responses may vary.

community Could fatty liver(other issues related to it..)play a role in Dupa/Aga?

in Treatment 6 upvotes 1 year ago

Fatty liver and related issues may influence hair loss conditions like Dupa/Aga. Treatments discussed include Minoxidil, finasteride, RU58841, myo-inositol, and L-glutamine.

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