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GlossaryHematopoietic Stem Cells

produce all types of blood cells in bone marrow

Hematopoietic Stem Cells (HSCs) are a type of stem cell found in the bone marrow that are responsible for producing all the different types of blood cells, including red blood cells, white blood cells, and platelets. These cells have the unique ability to both self-renew, creating more HSCs, and differentiate into various specialized blood cells, making them crucial for maintaining a healthy and functional blood system.

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research Hematopoietic Stem Cells: Nature and Niche Nurture

2 citations , May 2021 in “Bioengineering”

Blood stem cells are diverse, influenced by many factors, and understanding them is key for progress in regenerative medicine.

research Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair

24 citations , May 2016 in “Stem Cell Reviews and Reports”

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

research Stem Cells and the Circadian Clock

75 citations , September 2017 in “Developmental biology”

The circadian clock influences the behavior and regeneration of stem cells in the body.

research Stem Cells in Tissue Engineering

3 citations , January 2014 in “Elsevier eBooks”

Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.

research Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche

6 citations , May 2013 in “PloS one”

The Foxn1(-/-) nude mouse shows disrupted and expanded skin stem cell areas due to high Lhx2 levels.

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community Painkillers May Block Minoxidil

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Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.