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Glossary Hematopoietic Stem Cells

produce all types of blood cells in bone marrow

Hematopoietic Stem Cells (HSCs) are a type of stem cell found in the bone marrow that are responsible for producing all the different types of blood cells, including red blood cells, white blood cells, and platelets. These cells have the unique ability to both self-renew, creating more HSCs, and differentiate into various specialized blood cells, making them crucial for maintaining a healthy and functional blood system.

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research Identification of Transcripts Commonly Expressed in Both Hematopoietic and Germ-Line Stem Cells

14 citations , February 2008 in “Stem Cells and Development”

This study identified several genes highly expressed in germ-line stem cells that are also common in hematopoietic stem cells, potentially aiding the exploration of fundamental stem cell commonalities.

research Amelanocytic Anhidrotic Alopecia Areata-like Phenotype After Allogeneic Hematopoietic Cell Transplant

5 citations , August 2012 in “Archives of Dermatology”

This case report describes a man's permanent skin and hair whitening, and generalized anhidrosis following allogeneic stem cell transplant, linked to immune-mediated destruction of melanocytes.

research Permanent chemotherapy-induced alopecia after hematopoietic stem cell transplantation treated with low-dose oral minoxidil

4 citations , February 2022 in “JAAD case reports”

This case report describes a patient with permanent chemotherapy-induced alopecia who experienced full hair regrowth after treatment with low-dose oral minoxidil.

Successful Allogeneic Epidermal Grafting of Chronic Recessive Dystrophic Epidermolysis Bullosa Wounds from Hematopoietic Cell Donors in the Outpatient Setting

research 577 Successful allogeneic epidermal grafting of chronic recessive dystrophic epidermolysis bullosa wounds from hematopoietic cell donors in the outpatient setting

April 2019 in “Journal of Investigative Dermatology”

This study found that post-hematopoietic cell transplantation epidermal grafting significantly reduced chronic wound size in patients with recessive dystrophic epidermolysis bullosa.

A Case of Red Lunulae After Hematopoietic Stem Cell Transplantation

research A case of red lunulae after haematopoietic stem cell transplantation

May 2018 in “European Journal of Dermatology”

Adjusting the medication tacrolimus resolved a boy's red nail beds after a stem cell transplant.

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Learn

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learn Stem Cell Factor

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community Painkillers May Block Minoxidil

12 upvotes 1 year ago

Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

community Finasteride - 5 years and my expierience

128 upvotes 1 week ago

A 26-year-old shared their 5-year experience using finasteride and minoxidil for hair loss, noting initial improvements but later experiencing reduced libido and erection quality, leading them to switch from oral to topical finasteride. They advise starting with a low-dose topical solution and emphasize making informed decisions, acknowledging that while finasteride is effective, it can have side effects.

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