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GlossaryHematopoietic Stem Cells

produce all types of blood cells in bone marrow

Hematopoietic Stem Cells (HSCs) are a type of stem cell found in the bone marrow that are responsible for producing all the different types of blood cells, including red blood cells, white blood cells, and platelets. These cells have the unique ability to both self-renew, creating more HSCs, and differentiate into various specialized blood cells, making them crucial for maintaining a healthy and functional blood system.

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research Hematopoietic Stem Cells: Nature and Niche Nurture

2 citations, May 2021 in “Bioengineering”

Blood stem cells are diverse, influenced by many factors, and understanding them is key for progress in regenerative medicine.

research Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche

695 citations, October 2011 in “Cell stem cell”

Low oxygen areas help maintain and protect blood stem cells by using a simple sugar breakdown process for energy and managing their activity levels.

research Activation of Wnt Signaling in Hematopoietic Regeneration

49 citations, February 2008 in “Stem Cells”

Wnt10b helps blood stem cells grow after injury.

research Stem Cells in the Body

November 2017

Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.

research Transdifferentiation of Human Hair Follicle Mesenchymal Stem Cells into Red Blood Cells by OCT4

15 citations, January 2015 in “Stem cells international”

Human hair follicle stem cells can be turned into red blood cells.

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community Painkillers May Block Minoxidil

in Research/Science 15 upvotes 2 weeks ago

Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.