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Research

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research Mice humanised for the EGF receptor display hypomorphic phenotypes in skin, bone and heart

125 citations , August 2003 in “Development”

In this study, mice engineered to express human EGFR showed tissue-specific growth defects and neurodegeneration rescue, but developed severe heart issues and accelerated bone cell differentiation.

research Transplantation immunology: Solid organ and bone marrow

139 citations , February 2010 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

This review outlines the advancements in organ and tissue transplantation since the discovery of the human MHC and reports no new clinical results.

research Heat stress decreased hair follicle population in rex rabbits

10 citations , December 2018 in “Journal of animal physiology and animal nutrition”

This study found that heat stress in rex rabbits decreased hair follicle density and suppressed related signaling pathways, potentially affecting hair follicle development.

Isoproterenol Directs Hair Follicle-Associated Pluripotent (HAP) Stem Cells to Differentiate In Vitro to Cardiac Muscle Cells Which Can Be Induced to Form Beating Heart-Muscle Tissue Sheets

research Isoproterenol directs hair follicle-associated pluripotent (HAP) stem cells to differentiate in vitro to cardiac muscle cells which can be induced to form beating heart-muscle tissue sheets

29 citations , March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)”

This study observed that isoproterenol directs hair-follicle-associated pluripotent stem cells to differentiate into cardiac muscle cells in large numbers, forming tissue sheets of beating heart muscle cells in culture.

The Stag as a Historical Source of Materia Medica

research The stag as an historical source of materia medica

January 2023 in “Acta historiae medicinae stomatologiae pharmaciae medicinae veterinariae”

This article reviews historical uses of male red deer parts in traditional medicine but provides no new research findings; it emphasizes their long-standing role in treatments for various health issues.

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Community Join

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community Is RU558841 actually related to heart issues?

in Finasteride/Dutasteride 11 upvotes 1 year ago

RU58841 may cause heart-related side effects like palpitations and chest pain, though evidence is mostly anecdotal. Users report mixed experiences, with some stopping due to side effects and others using it without issues, but concerns about its safety and sourcing remain.

community Dutasteride likely reduces Bone Mineral Density

in Research/Science 5 months ago

Dutasteride may reduce bone mineral density, but there's no increased risk of osteoporosis or fractures compared to finasteride. Users suggest resistance training to counter potential bone effects.

community Some of y’all need to hear this

in Chat 351 upvotes 3 years ago

Understanding that the importance of hair loss should not be overstated and encouraging self-love and confidence regardless of physical appearance. People discussed how they were feeling about their own hair loss and shared tips on treatments like Minoxidil, Finasteride and RU58841.

community RU-58841 Lung Disease Possibility | Chest pain, "heart issues", etc

20 upvotes 2 years ago

Some users of RU-58841 report cardiovascular symptoms like heart palpitations and chest tightness, which may be linked to its metabolites causing lung disease. The safety of RU-58841 is uncertain due to lack of long-term data and concerns about product purity, especially from gray market sources.

community Anyone tried Tretinoin? I’ve heard great things

22 upvotes 2 years ago

People discuss using Tretinoin for both skin anti-aging and improving hair loss treatments. They mention combining Tretinoin with Minoxidil to enhance its effectiveness for hair growth.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn GHK-Cu

Heard alopecia areata leaves scar-like spots? Some peptides are helping those areas regrow hair. Alopecia areata patches usually still have living follicles. Peptides are being studied as a possible add-on, but the evidence is small and early. See a dermatologist for treatment.

learn capsicum

Can the heat from capsicum actually wake up dormant hair follicles? Capsicum heat may stimulate dormant hair follicles through increased blood flow and growth factors.

learn Minoxidil

What are the side effects of minoxidil, and can oral minoxidil affect your heart? Minoxidil can cause side effects, and because it was designed as a blood-pressure drug, some of them involve the heart and circulation. Published studies of low-dose oral minoxidil describe mostly mild problems, but fluid around the heart, pericarditis and other serious events have been reported, and the long-term picture is still being studied. Do not start, stop or change minoxidil without a doctor, and if you develop chest pain, a racing heartbeat, shortness of breath, fainting, swelling or rapid weight gain while using it, stop and seek medical care.

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Clinics

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